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Dual delivery of hydrophilic and hydrophobic drugs from chitosan/diatomaceous e...

López-Cebral, Rita; Peng, Guangjia; Reys, Lara L.; Silva, Simone Santos; Oliveira, Joaquim M.; Chen, Jie; Silva, Tiago José Quinteiros Lopes Henriques

Oral administration of drugs presents important limitations, which are frequently not granted the importance that they really have. For instance, hepatic metabolism means an important drug loss, while some patients have their ability to swell highly compromised (i.e. unconsciousness, cancer...). Sublingual placement of an accurate Pharmaceutical Dosage Form is an attractive alternative. This work explores the u...


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