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Iron status is associated with mood, cognition, and functional ability in older...
Portugal-Nunes, Carlos; Castanho, Teresa Costa; Amorim, Liliana; Moreira, Pedro Silva; Mariz, José; Marques, Fernanda; Sousa, NunoSeveral conditions are risk factors for iron deficiency (ID), some of which are highly prevalent in older individuals. Despite the amount of evidence pointing for a role of ID in cognition, mood and physical functional ability, the research addressing these associations in older individuals is still scarce. In the present study, 162 older community-dwelling individuals (29.53% classified as ID) were enrolled in...
The resting-brain of obsessive-compulsive disorder
Moreira, Pedro Silva; Marques, Paulo; Magalhães, Ricardo; Esteves, Madalena; Sousa, Nuno; Soares, José Miguel; Morgado, PedroObsessive–compulsive disorder (OCD) is one of the most debilitating psychiatric conditions, having a dramatic impact on patients’ daily living. In this work, we aimed to explore resting-state functional connectivity in OCD patients, using an independent component analysis. Eighty individuals (40 patients and 40 healthy controls) performed a resting state fMRI protocol. OCD patients displayed reduced functional ...
Relationship between obsessive compulsive disorder and cortisol: Systematic rev...
Lima, João; Moreira, Pedro Silva; Lima, Catarina Raposo Oliveira; Sousa, Nuno; Morgado, PedroAltered stress response and consequent elevated levels of circulating glucocorticoids have been found in neuropsychiatric disorders such as depression or anxiety disorders and proposed to also play a role in the pathophysiology of obsessive-compulsive disorder (OCD). Despite the observation that stressful events may precede the disease onset or even exacerbate its symptoms, studies in this field do not always r...
Anatomic and non-anatomic reconstruction improves post-operative outcomes in ch...
Xará-Leite, Francisco; Andrade, Renato; Moreira, Pedro Silva; Coutinho, Luís; Ayeni, Olufemi R.; Sevivas, Nuno; Espregueira-Mendes, JoãoTo systematize the surgical outcomes of anatomic and non-anatomic reconstruction in patients with chronic acromio-clavicular joint (ACJ) instability and determine which technique is superior. Purpose To systematize the surgical outcomes of anatomic and non-anatomic reconstruction in patients with chronic acromio-clavicular joint (ACJ) instability and determine which technique is superior. Methods This review wa...
Validation of wireless sensors for psychophysiological studies
Moreira, Pedro Silva; Chaves, Pedro; Dias, Ruben; Dias, Nuno; Almeida, Pedro R.James One (MindProber Labs) is a wireless psychophysiological device comprising two sensors: one measuring electrodermal activity (EDA), the other photoplethysmography (PPG). This paper reports the validation of James One's EDA sensor by comparing its signal against a research grade polygraph. Twenty participants were instructed to perform breathing exercises to elicit the modulation of EDA and heart rate, whil...
Poor sleep quality associates with decreased functional and structural brain co...
Amorim, Liliana; Magalhães, Ricardo; Coelho, Ana; Moreira, Pedro Silva; Portugal-Nunes, Carlos; Castanho, Teresa Costa; Marques, Paulo; Sousa, NunoSleep is a ubiquitous phenomenon, essential to the organism homeostasis. Notwithstanding, there has been an increasing concern with its disruption, not only within the context of pathological conditions, such as neurologic and psychiatric diseases, but also in health. In fact, sleep complaints are becoming particularly common, especially in middle-aged and older adults, which may suggest an underlying susceptib...