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Angiogenic factors: role in esophageal cancer, a brief review
Ladeira, Kátia; Macedo, Filipa; Longatto, Adhemar; Martins, SandraEsophageal cancer has an aggressive behavior with rapid tumor mass growth and frequently poor prognosis; it is known as one of the most fatal types of cancer worldwide. The identification of potential molecular markers that can predict the response to treatment and the prognosis of this cancer has been subject of a vast investigation in the recent years. Among several molecules, various angiogenic factors that ...
Gastric cancer treated with pressurized intraperitoneal aerosol chemotherapy: r...
Macedo, Filipa; Ladeira, Kátia; Longatto, Adhemar; Martins, SandraAim: Gastric cancer is the cancer with the highest rate of peritoneal metastization and this type of spread is associated with a higher death rate compared to distant organ metastasis. The systemic chemotherapy has a minimal effect in peritoneal metastasis so new types of treatment have emerged. The authors revised the main studies done in pressurized intraperitoneal aerosol chemotherapy (PIPAC) and presented t...
Gastric Cancer and Angiogenesis: Is VEGF a Useful Biomarker to Assess Progressi...
Macedo, Filipa; Ladeira, Kátia; Longatto, Adhemar; Martins, Sandra F.Gastric cancer (GC) has high mortality owing to its aggressive nature. Tumor angiogenesis plays an essential role in the growth, invasion, and metastatic spread of GC. The aim of this work was to review the angiogenic biomarkers related to the behavior of GC, documented in the literature. A search of the PubMed database was conducted with the MeSH terms: "Stomach neoplasms/blood [MeSH] or stomach neoplasms/bloo...