4 documents found, page 1 of 1
Explaining RANKL inhibition by OPG through quantum biochemistry computations an...
Sousa, Bruno Lopes de; Barroso Neto, Ito Liberato; Oliveira, Evanildo Ferreira; Fonseca, Emerson Alberto da; Lima Neto, Pedro de; Ladeira, Luiz OrlandoOsteoporosis is a degenerative disease associated with excessive bone resorption, a natural process performed by osteoclasts. In turn, osteoclast maturation is critically regulated by the receptor activator of nuclear factor kB ligand (RANKL), its signalling receptor (RANK), and its decoy receptor osteoprotegerin (OPG). The critical role of the protein triad, RANK–RANKL–OPG, in osteoclastogenesis has made their...
Neurotoxicity in zebrafish exposed to carbon nanotubes: Effects on neurotransmi...
Rocha, A. M. da; Kist, L. W.; Almeida, E. A. [UNESP]; Silva, D. G. H. [UNESP]; Bonan, C. D.; Altenhofen, S.; Kaufmann Jr, C. G.; Bogo, M. R.Made available in DSpace on 2019-10-04T11:57:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-01; Instituto Nacional de Ciencia e Tecnologia Nanomaterial de Carbono; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Given the increasing use of carbon nanotubes (CNT) in several industries and technological applications, it is essential to perform in vivo toxicological studies with...
Enzymatic extract containing lignin peroxidase immobilized on carbon nanotubes:...
Oliveira, Sabrina Feliciano; Luz, José Maria Rodrigues da; Kasuya, Maria Catarina Megumi; Ladeira, Luiz Orlando; Correa Junior, AryThe majority of the textile dyes are harmful to the environment and potentially carcinogenic. Among strategies for their exclusion, the treatment of dye contaminated wastewater with fungal extract, containing lignin peroxidase (LiP), may be useful. Two fungi isolates, Pleurotus ostreatus (PLO9) and Ganoderma lucidum (GRM117), produced the enzymatic extract by fermentation in the lignocellulosic residue, Jatroph...
Efficient delivery of DNA into bovine preimplantation embryos by multiwall carb...
Munk, Michele; Ladeira, Luiz Orlando; Carvalho, Bruno Campos de; Raposo, Nádia Rezende Barbosa; Serapião, Raquel V.; Quintão, Carolina Capobiango RomanoThe pellucid zone (PZ) is a protective embryonic cells barrier against chemical, physical or biological substances. This put, usual transfection methods are not efficient for mammal oocytes and embryos as they are exclusively for somatic cells. Carbon nanotubes have emerged as a new method for gene delivery, and they can be an alternative for embryos transfection, however its ability to cross the PZ and mediate...