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Features associated with cognitive impairment and dementia in a community-based...
Guimarães,Henrique Cerqueira; Cascardo,Jorge Luiz; Beato,Rogério Gomes; Barbosa,Maira Tonidandel; Machado,Thais Helena; Almeida,Mariana Alves deABSTRACT A higher level of educational attainment constitutes a protective factor against cognitive decline in the elderly. Nevertheless, the elements underpinning this association are yet not fully understood. Objective: The primary aim of this study was to compare cognitively impaired illiterate elderly subjects with cognitively preserved counterparts, according to demographics, comorbidities, lifetime habits...
Analysis of a case series of behavioral variant frontotemporal dementia: Emphas...
Guimarães,Henrique Cerqueira; Vale,Thiago Cardoso; Pimentel,Victor; de Sá,Nayara Carvalho; Beato,Rogério Gomes; Caramelli,PauloABSTRACT Introduction: Despite many advances in the characterization of the behavioral variant of frontotemporal dementia (bvFTD), the diagnosis of this syndrome poses a significant challenge, while delays or diagnostic mistakes may impact the proper clinical management of these patients. Objective: To describe the clinical profile at first evaluation of a sample of patients with bvFTD from a specialized outpat...
The Pietà study: epidemiological investigation on successful brain aging in Cae...
Caramelli,Paulo; Barbosa,Maira Tonidandel; Sakurai,Emília; Santos,Etelvina Lucas dos; Beato,Rogério Gomes; Machado,João Carlos BarbosaOBJECTIVES: To present the methods and baseline characteristics of the Pietà study, a population-based survey investigating successful brain aging in the oldest-old. METHOD: The study was conducted in Caeté (MG), Brazil. In 2007, 1,251 individuals aged 75+ years were living in the city and were invited to participate. Participants responded to a general health questionnaire and were submitted to clinical, neuro...
Epilepsia e demência em uma amostra de pacientes idosos acompanhados em serviço...
Almeida,Mariana Alves de; Fonseca,Simone Rios; Santos,Ana Paula Borges; Guimarães,Henrique Cerqueira; Corrêa,Thiago André Fuscaldi; Beato,Rogério GomesOBJETIVO: Determinar a freqüência de epilepsia em uma amostra ambulatorial de pacientes idosos com demência e analisar possível associação da epilepsia a uma causa específica de demência. METODOLOGIA: Estudo retrospectivo com dados de 135 pacientes com demência acompanhados em ambulatório de Neurologia Cognitiva, no período de setembro de 2006 a novembro de 2007. Foi realizado levantamento de dados clínicos, la...
Dementia caregiver burden in a Brazilian sample: Association to neuropsychiatri...
Fialho,Patrícia Paes Araujo; Koenig,Anne Marise; Santos,Etelvina Lucas dos; Guimarães,Henrique Cerqueira; Beato,Rogério Gomes; Carvalho,Viviane AmaralAbstract Taking care of elderly demented individuals, especially when they present behavioral changes, can be very exhaustive for both family and caregivers. Generally, this leads to changes in the family lifestyle, and the caregiver must deal with a range of problems. Information on this topic in Latin America, including Brazil, remains scarce. Objective: To investigate the relationship between the presence of...
Neurobiology of apathy in Alzheimer's disease
Guimarães,Henrique Cerqueira; Levy,Richard; Teixeira,Antônio Lúcio; Beato,Rogério Gomes; Caramelli,PauloApathy is considered the most frequent neuropsychiatric disturbance in dementia and its outcome is generally deleterious. Apathy can be related to a dysfunction of the anatomical-system that supports the generation of voluntary actions, namely the prefrontal cortex and/or the prefrontal-subcortical circuits. In Alzheimer's disease, pathological and neuroimaging data indicate that apathy is likely due to a dysfu...
Subjective memory complaints and cognitive performance in a sample of healthy e...
Caramelli,Paulo; Beato,Rogério GomesAbstract Memory loss is a major complaint among the elderly population. However, the clinical significance of this symptom is variable and also controversial in the scientific literature. Objective: To compare the cognitive performance of two groups of healthy elderly, one group with and the other without, subjective memory complaints (SMC). Methods: Sixty cognitively intact elderly individuals (39 females and ...
Perfil neuropsiquiátrico na doença de Alzheimer e na demência mista
Fonseca,Simone Rios; Santos,Ana Paula Borges; Almeida,Mariana Alves de; Guimarães,Henrique Cerqueira; Corrêa,Thiago André Fuscaldi; Beato,Rogério GomesAlguns estudos sugerem que infartos cerebrais possam agravar a demência em pacientes com doença de Alzheimer (DA) e que sintomas neuropsiquiátricos sejam comuns tanto na DA quanto na demência vascular (DV). Doença cerebrovascular concomitante à DA incorre na chamada demência mista (DM). OBJETIVOS: Comparar a freqüência e o perfil dos sintomas neuropsiquiátricos em uma amostra de pacientes com DA e DM. MÉTODOS: ...
Brazilian version of the Frontal Assessment Battery (FAB): Preliminary data on ...
Beato,Rogério Gomes; Nitrini,Ricardo; Formigoni,Ana Paula; Caramelli,PauloAbstract The Frontal Assessment Battery (FAB) has been proposed as a diagnostic tool for patients with frontal lobe syndrome. Objectives: To present the Brazilian version of the FAB and to show preliminary data on the performance of healthy elderly in the battery, correlating with age, education and scores in the MiniMental State Examination (MMSE). Methods: Forty-eight healthy elderly individuals (34 female/14...