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An Overview of Wound Dressing Materials
Lagoa, Tânia; Queiroga, MC; Martins, LWounds are an increasing global concern, mainly due to a sedentary lifestyle, frequently associated with the occidental way of life. The current prevalence of obesity in Western societies, leading to an increase in type II diabetes, and an elderly population, is also a key factor associated with the problem of wound healing. Therefore, it stands essential to find wound dressing systems that allow for reestablis...
Microbiota Modulation as an Approach to Prevent the Use of Antimicrobials Assoc...
Lagoa, Tânia; Martins, Luís; Queiroga, Maria CristinaModern lifestyle factors—such as dietary changes, reduced microbial exposure, and ge- netic susceptibility—profoundly influence the composition and function of the commensal microbiota. Additionally, dysregulation of the gut microbiota has been linked to impaired immune responses and an increased prevalence of skin disorders, including allergies and in- flammatory conditions, thereby underscoring the importance...
An Overview of Wound Dressing Materials
Lagoa, Tânia; Queiroga, Cristina; Martins, LuísWounds are an increasing global concern, mainly due to a sedentary lifestyle, frequently associated with the occidental way of life. The current prevalence of obesity in Western societies, leading to an increase in type II diabetes, and an elderly population, is also a key factor associated with the problem of wound healing. Therefore, it stands essential to find wound dressing systems that allow for reestablis...
Study of the intestinal microbiome of healthy and atopic dogs.
Lagoa, Tânia; Conceição, Sara; Laranjo, Marta; Martins, Luís; Queiroga, CristinaIntroduction: Atopic dermatitis is the most common chronic pruritic inflammatory skin condition with a high impact on public health. This study proposes that the development of atopic dermatitis (AD), is associated with dysbiosis, not only of the skin microbiome, but also of the gut flora, or microbiota. Therefore, imbalances in commensal bacteria can negatively impact the immune system response and lead to inf...
Microbiota Modulation as an Approach to Prevent the Use of Antimicrobials Assoc...
Lagoa, Tânia; Martins, Luís; Queiroga, CristinaModern lifestyle factors—such as dietary changes, reduced microbial exposure, and genetic susceptibility—profoundly influence the composition and function of the commensal microbiota. Additionally, dysregulation of the gut microbiota has been linked to impaired immune responses and an increased prevalence of skin disorders, including allergies and inflammatory conditions, thereby underscoring the importance of ...
Development of a canine epidermis equivalent model for evaluation of sensitization
Marques, M; Nunes, J; Ustymenko, B; Lagoa, Tânia; Fialho, Luísa; Martins, Luís; Burke, Anthony; Souza, E; Filho, César; Craveiro, Alexandre; Costa, AnaBackground Canine atopic dermatitis (cAD) is a genetic-predisposed allergic and pruritic inflammatory skin condition, associated with sensitization to environmental allergens. Keratinocytes can produce several inflammatory mediators, in response to several other host mediators, antigens, and pathogens by virtue of their wide range of surface receptors, some of them dysregulated in cAD individuals. A histotypica...
Agora as feridas! Hydrogel on cells: ok! What about application on wounds? Expe...
Lagoa, Tânia; Queiroga, Maria Cristina; Branco, Sandra; Martins, LuísAs feridas cutâneas, maioritariamente as produzidas por abrasão, requerem suporte cicatrizante, visando a antissepsia e a manutenção de um ambiente húmido. Após a testagem da formulação de hidrogel em modelo cultural epidérmico, passou-se ao ensaio em pele de caninos, que haviam sofrido feridas abrasivas acidentais. A evolução das feridas foi avaliada, reportada e as opções resolutivas foram discutidas.