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Development of a standardized histopathology scoring system for intervertebral ...

Gullbrand, SE; Ashinsky, BG; Lai, A; Gansau, J; Crowley, J; Cunha, C; Engiles, JB; Fusellier, M; Muehleman, C; Pelletier, M; Presciutti, S; Schol, J

Background: The rabbit lumbar spine is a commonly utilized model for studying intervertebral disc degeneration and for the pre-clinical evaluation of regenerative therapies. Histopathology is the foundation for which alterations to disc morphology and cellularity with degeneration, or following repair or treatment are assessed. Despite this, no standardized histology grading scale has yet been established for t...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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