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Cardiovascular effects of rivaroxaban in heart failure patients with sinus rhyt...

Sharma, Abhinav; Caldeira, Daniel; Razaghizad, Amir; Pinto, Fausto J.; van Veldhuisen, Dirk J.; Mehra, Mandeep R.; Lam, Carolyn S. P.; Cleland, John

Background: There is inconsistency in the relationship between sleeping measures and the occurrence of soccer injuries. Further, most studies investigated sleeping quantity and quality during soccer season but not during off-season. The purpose of this study was to determine the influence of sleeping off-season and during soccer season on the occurrence of injuries in professional soccer players. It was hypothe...


Randomized trials fit for the 21st century. A joint opinion from the European S...

Bowman, Louise; Weidinger, Franz; Albert, Michelle A.; Fry, Edward T. A.; Pinto, Fausto J.; Achenbach, Stephan; Bowman, Louise; Casadei, Barbara

Randomized controlled trials are the cornerstone for reliably evaluating therapeutic strategies. However, during the past 25 years, the rules and regulations governing randomized trials and their interpretation have become increasingly burdensome, and the cost and complexity of trials has become prohibitive. The present model is unsustainable, and the development of potentially effective treatments is often sto...


Cardiovascular risk factors and clinical outcomes among patients hospitalized w...

Prabhakaran, Dorairaj; Singh, Kavita; Kondal, Dimple; Raspail, Lana; Mohan, Bishav; Kato, Toru; Sarrafzadegan, Nizal; Talukder, Shamim Hayder

Background and aims: Limited data exist on the cardiovascular manifestations and risk factors in people hospitalized with COVID-19 from low- and middle-income countries. This study aims to describe cardiovascular risk factors, clinical manifestations, and outcomes among patients hospitalized with COVID-19 in low, lower-middle, uppermiddle- and high-income countries (LIC, LMIC, UMIC, HIC). Methods: Through a pro...


World Heart Federation roadmap for digital health in cardiology

Tromp, Jasper; Jindal, Devraj; Redfern, Julie; Bhatt, Ami; Séverin, Tania; Banerjee, Amitava; Ge, Junbo; Itchhaporia, Dipti; Jaarsma, Tiny

More than 500 million people worldwide live with cardiovascular disease (CVD). Health systems today face fundamental challenges in delivering optimal care due to ageing populations, healthcare workforce constraints, financing, availability and affordability of CVD medicine, and service delivery. Digital health technologies can help address these challenges. They may be a tool to reach Sustainable Development Go...


Improved cardiac and venous pressures during hospital stay in patients with acu...

Akiyama, Eiichi; Cinotti, Raphaël; Čerlinskaitė, Kamilė; Van Aelst, Lucas N. L.; Arrigo, Mattia; Plácido, Rui; Chouihed, Tahar; Girerd, Nicolas

Aims: Changes in echocardiographic parameters and biomarkers of cardiac and venous pressures or estimated plasma volume during hospitalization associated with decongestive treatments in acute heart failure (AHF) patients with either preserved left ventricular ejection fraction (LVEF) (HFPEF) or reduced LVEF (HFREF) are poorly assessed. Methods and results: From the metabolic road to diastolic heart failure: dia...


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