78 documents found, page 1 of 8
Host−guest complexes of cyclopentadienyl iron dicarbonyl (CpFe(CO)2) CO-releasi...
Monteiro, Rodrigo P.; Calhau, Isabel B.; Gomes, Ana C.; Mendes, Ricardo F.; Paz, Filipe A. Almeida; D. Lopes, André; Da Silva, José PauloIron(II) cyclopentadienyl carbonyl complexes are promising as CO-releasing molecules (CORMs) for therapeutic applications. In common with other metallodrugs, the practical application of Fe-CORMs may require their conjugation with biocompatible carriers to improve their bioavailability and protect them from premature degradation. Here, we show that the CO-releasing properties of the complexes [CpFe(CO)2Cl] (1) ...
Inclusion complexes of cucurbit[n]urils (n = 7, 8) with η5 -cyclopentadienyl me...
Neves, Patrícia; Gomes, Ana C.; Monteiro, Rodrigo P.; Santos, Mirela J.; Valente, Anabela A.; D. Lopes, André; Gonçalves, Isabel S.; Pillinger, MartynThere are very few known examples of supramolecular compounds comprising molybdenum species hosted inside the portals/cavities of cucurbit[n]urils (CBn). In this work, CB7 and CB8 macrocycles have been studied as hosts for the carbonyl complex [CpMo(CO)(3)Me] (1) (Cp = eta(5)-C5H5). Compounds were isolated in the solid state and characterized as genuine 1:1 inclusion complexes (1@CBn) by elemental and thermogra...
Host-guest complexes of cucurbit[8]uril and [(η5-C5H4R)Mo(CO)3CH3] (R = H, CO2C...
Gomes, Ana C.; Monteiro, Rodrigo P.; Calhau, Isabel B.; D. Lopes, André; Gonçalves, Isabel S.; Pillinger, MartynThe monosubstituted cyclopentadienyl half-sandwich molybdenum(II) tricarbonyl complex [(eta 5-C5H4CO2CH3) Mo(CO)3CH3] (1) and its 1:1 inclusion compound with cucurbit[8]uril (1@CB8) have been prepared and characterised by elemental and thermogravimetric analyses, powder X-ray diffraction, diffuse reflectance UV-vis, solid-state 13C{1H} MAS NMR, FT-IR, and Raman spectroscopies. The CO-releasing behaviours of 1, ...
Host-guest complexes of cucurbit[8]uril and [(η5-C5H4R)Mo(CO)3CH3] (R = H, CO2C...
Gomes, Ana C.; Monteiro, Rodrigo P.; Calhau, Isabel B.; Lopes, André D.; Gonçalves, Isabel S.; Pillinger, MartynThe monosubstituted cyclopentadienyl half-sandwich molybdenum(II) tricarbonyl complex [(η5 -C5H4CO2CH3) Mo(CO)3CH3] (1) and its 1:1 inclusion compound with cucurbit[8]uril (1@CB8) have been prepared and characterised by elemental and thermogravimetric analyses, powder X-ray diffraction, diffuse reflectance UV–vis, solid-state 13C{1 H} MAS NMR, FT-IR, and Raman spectroscopies. The CO-releasing behaviours of 1, 1...
An organic-organometallic CO-releasing material comprising 4,4'-bipyridine and ...
Calhau, Isabel B.; Gomes, Ana C.; Mendes, Ricardo F.; Almeida Paz, Filipe A.; Gonçalves, Isabel S.; Pillinger, MartynOver the past two decades, following the discovery of the important biological roles of carbon monoxide (CO), metal carbonyl complexes have been intensively studied as CO-releasing molecules (CORMs) for therapeutic applications. To improve the properties of "bare" low molecular weight CORMs, attention has been drawn to conjugating CORMs with macromolecular and inorganic scaffolds to produce CO-releasing materia...
Inclusion complexes of cucurbit[n]urils (n = 7, 8) with η5‐cyclopentadienyl met...
Neves, Patrícia; Gomes, Ana C.; Monteiro, Rodrigo P.; Santos, Mirela J.; Valente, Anabela A.; Lopes, André D.; Gonçalves, Isabel S.; Pillinger, MartynThere are very few known examples of supramolecular compounds comprising molybdenum species hosted inside the portals/cavities of cucurbit[n]urils (CBn). In this work, CB7 and CB8 macrocycles have been studied as hosts for the carbonyl complex [CpMo(CO)3Me] (1) (Cp = η5-C5H5). Compounds were isolated in the solid state and characterized as genuine 1:1 inclusion complexes (1@CBn) by elemental and thermogravimetr...
Effect of 4,4′-dialkyl-2,2′-bipyridine ligands on the hydrolysis of dichlorodio...
Gomes, Diana M.; Gomes, Ana C.; Neves, Patrícia; Almeida Paz, Filipe A.; Valente, Anabela A.; Gonçalves, Isabel S.; Pillinger, MartynMolybdenum catalysts have been industrially recognized for decades for liquid phase epoxidation, which is an important chemical reaction process, since epoxides are used for many industrial applications. In this work, molybdenum oxide hybrid catalysts, prepared by a reflux hydrolysis methodology, performed effectively as heterogeneous catalysts or reaction-induced self-separating catalysts under mild reaction c...
A Molybdenum(VI) Complex of 5-(2-pyridyl-1-oxide)tetrazole: synthesis, structur...
Nunes, Martinique S.; Gomes, Diana M.; Gomes, Ana C.; Neves, Patrícia; Mendes, Ricardo F.; Paz, Filipe A. Almeida; Lopes, Andre D.; Pillinger, MartynThe discovery of heterogeneous catalysts synthesized in easy, sustainable ways for the valorization of olefins derived from renewable biomass is attractive from environmental, sustainability, and economic viewpoints. Here, an organic–inorganic hybrid catalyst formulated as [MoO3 (Hpto)]·H2O (2), where Hpto = 5-(2-pyridyl-1-oxide)tetrazole, was prepared by a hydrolysis– condensation reaction of the complex [MoO2...
Molybdenum(VI) complexes with ligands derived from 5-(2-pyridyl)-2H-tetrazole a...
Nunes, Martinique S.; Gomes, Ana C.; Neves, Patrícia; Mendes, Ricardo F.; Almeida Paz, Filipe A.; Lopes, André; Pillinger, Martyn; Gonçalves, Isabel S.The development of effective catalytic epoxidation processes that are an alternative to stoichiometric non-selective oxidation routes is important to meet environmental sustainability goals. In this work, molybdenum (VI) compounds bearing 5-(2-pyridyl)-2H-tetrazole derivatives as organic components, namely the ionic and neutral mononuclear complexes (H2ptz)[MoO2Cl2(ptz)] (1) and [MoO2Cl2(tBu-ptz)] (2), and the ...
Effect of β-cyclodextrin on the CO release kinetics and antimicrobial activity ...
Monteiro, Rodrigo P.; Calhau, Isabel B.; Gomes, Ana C.; Pereira, Carla; Vieira, Cátia; Faustino, M. Amparo F.; Almeida, Adelaide; Pillinger, MartynIn the present work the possibility of improving the solubility, bioavailability and bactericidal activity of the carbon monoxide releasing molecule (CORM) [Mo(CO)5Br]− (as its tetraethylammonium salt) (1) by solvent-free co-grinding with β-cyclodextrin (βCD) in a planetary ball mill was investigated. Data obtained by FT-IR spectroscopy, Raman spectroscopy, powder X-ray diffraction and thermogravimetric analysi...