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Pneumatocele Gigante: Um Achado Inesperado

Fevereiro, MC; Cardoso, S; Lampreia, F; Godinho, A


Miocardiopatia de Takotsubo: na Origem do Choque Cardiogénico

Fevereiro, MC; Simões, I; Lampreia, F; Marcão, I; Godinho, A; Lopes, V

A miocardiopatia de Takotsubo, de etiologia desconhecida, caracteriza-se pela disfunção sistólica súbita e transitória dos segmentos médio-apicais do ventrículo esquerdo, sem doença coronária significativa, com total normalização das alterações segmentares. É mais frequente em mulheres de meia-idade, implicando diagnóstico diferencial com a sindrome coronária aguda. Apresentamos o caso de uma mulher de 59 anos ...


Long-Term Maraviroc Use As Salvage Therapy in HIV-2 Infection

Caixas, U; Ferreira, J; Marinho, A; Faustino, I; Grilo, N; Lampreia, F; Germano, I; Monteiro, E; Pereira, S


Effect of efavirenz on high-density lipoprotein antioxidant properties in HIV-i...

Pereira, S; Batuca, J; Caixas, U; Branco, T; Delgado-Alves, J; Germano, I; Lampreia, F; Monteiro, E

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: * In previous work, we showed a long-term and concentration-dependent beneficial effect of the non-nucleoside reverse transcriptase inhibitor efavirenz (EFV) on high-density lipoproteins (HDL) in human immunodeficiency virus (HIV)-infected patients. * Furthermore, it has been suggested that instead of the current practice of only measuring HDL-chelesterol values, the ev...


Effect of Efavirenz on High-Density Lipoprotein Antioxidant Properties in HIV-I...

Pereira, SA; Batuca, JR; Caixas, U; Branco, T; Delgado-Alves, J; Germano, I; Lampreia, F; Monteiro, EC

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: * In previous work, we showed a long-term and concentration-dependent beneficial effect of the non-nucleoside reverse transcriptase inhibitor efavirenz (EFV) on high-density lipoproteins (HDL) in human immunodeficiency virus (HIV)-infected patients. * Furthermore, it has been suggested that instead of the current practice of only measuring HDL-chelesterol values, the ev...


Efavirenz concentrations in HIV-infected patients with and without viral hepatitis

Pereira, S; Caixas, U; Branco, T; Germano, I; Lampreia, F; Papoila, A; Monteiro, E

AIMS: Data on efavirenz in HIV/viral hepatitis co-infected patients is non-consensual, probably due to liver function heterogeneity in the patients included. METHODS: A case control study was performed on 27 HIV-infected patients, with controlled and homogenous markers of hepatic function, either mono-infected or co-infected with HBV/HCV, to ascertain the influence of viral hepatitis on efavirenz concentrations...


Efavirenz Concentrations in HIV-Infected Patients With and Without Viral Hepatitis

Pereira, SA; Caixas, U; Branco, T; Germano, I; Lampreia, F; Papoila, AL; Monteiro, E

AIMS: Data on efavirenz in HIV/viral hepatitis co-infected patients is non-consensual, probably due to liver function heterogeneity in the patients included. METHODS: A case control study was performed on 27 HIV-infected patients, with controlled and homogenous markers of hepatic function, either mono-infected or co-infected with HBV/HCV, to ascertain the influence of viral hepatitis on efavirenz concentrations...


Síndrome Retrovírica Aguda

Serrão, V; Caldas Lopes, L; Lampreia, F; Germano, I; Paiva Lopes, MJ

A síndrome retrovírica aguda ou infecção primária pelo Vírus da Imunodeficiência Humana (VIH), tem manifestações clínicas inespecíficas, sendo raramente diagnosticada. Como a sintomatologia pode ocorrer antes da formação de anticorpos detectáveis pelos testes classicamente utilizados, o diagnóstico deverá basear-se num elevado índice de suspeição clínica associado a um correcto pedido e interpretação dos testes...


Long-Term and Concentration-Dependent Beneficial Effect of Efavirenz on HDL-Cho...

Pereira, SA; Branco, T; Côrte-Real, R; Germano, I; Lampreia, F; Caixas, U; Monteiro, E

AIMS: To investigate the long-term effects of efavirenz on cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein (LDL-C) and triglycerides (TG). METHODS: Thirty-four HIV-infected patients who commenced efavirenz therapy were monitored for 36 months. RESULTS: In patients with baseline HDL-C<40 mg.dL-1 an increase in HDL-C from 31+/-1 mg.dL-1 to 44+/-2 mg.dL-1 (95% confidence int...


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