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Controversies in myopia control treatment: what does it mean for future research?

Lança, Carla; Repka, Michael X.; Grzybowski, Andrzej

Purpose: Treatment of myopia has been informed by more than 3 decades of clinical trials and other observations. However, controversies regarding myopia control remain, such as when to stop treatment and what is the long-term efficacy of treatment. This perspective aims to describe clinically relevant and current controversies regarding myopia treatment. Design: Perspective. Methods: We reviewed clinical trial ...


Validation of binocular vision and ocular surface assessment tools in digital e...

Barata, Maria João; Aguiar, Pedro; Grzybowski, Andrzej; Lança, Carla; jMoreira-Rosário, André

Background: To understand if binocular vision disorders are associated with Digital Eye Strain Syndrome (DESS), a study protocol is needed to ensure consistency across observational studies. This study aims to test the feasibility of a protocol to assess DESS, screen time, binocular vision, and dry eye. Methods: DESIROUS is an observational cross-sectional study among Polytechnic students at the Lisbon School o...


Spatial frequency of environments and myopia: a systematic review on associated...

Li, Dan-Li; Lança, Carla; Zhang, Xiu-Juan; Grzybowski, Andrzej; He, Xian-Gui; Pan, Chen-Wei

Purpose: Previous animal studies have found a relationship between spatial frequency and myopia. New research in humans suggests that reduced high spatial content of the visual environment may be a contributing factor to myopia development. This study aims to review the literature and elucidate the potential biological mechanisms linking spatial frequency and myopia. Methods: A systematic search was conducted a...


Presbyopia and age-related macular degeneration

Abel Szeps; Juan Manuel Suarez; Valeria Bordese; Matías Acerbi; Roberto Albertazzi; Guillermo Iribarren; José Luna Pinto; Lança, Carla; Rafael Iribarren

Objective: To evaluate the design of spectacle lenses and daily spectacle use in presbyopes over 60 years of age with and without age-related macular degeneration (AMD). Methods: A cross-sectional study was designed, and a web questionnaire was distributed to the two ophthalmological centers' database of presbyopic outpatients over 60 years of age with and without AMD. The questionnaire included monofocal, bifo...


Will the new anti-myopia spectacles be the standard of care in future?

Lança, Carla; Pan, Chen-Wei; Grzybowski, Andrzej

Reports of myopia increases across the world show an expanding growing public health problem. Myopia prevalence is exceptionally high in some continents, especially in Asia, particularly East Asian countries, but was also reported to have increased in other continents, such as North America and Europe, although there is considerable variation between geographic areas and racial groups in the myopia burden. The ...


Predicting children’s myopia risk: a Monte Carlo approach to compare the perfor...

Artiemjew, Piotr; Cybulski, Radosław; Emamian, Mohammad Hassan; Grzybowski, Andrzej; Jankowski, Andrzej; Lança, Carla; Mehravaran, Shiva

This study presents the initial results of the Myopia Risk Calculator (MRC) Consortium, introducing an innovative approach to predict myopia risk by using trustworthy machine-learning models. The dataset included approximately 7,945 records (eyes) from 3,989 children. We developed a myopia risk calculator and an accompanying web interface. Central to our research is the challenge of model trustworthiness, speci...


Myths in myopia epidemiology and treatment

Lança, Carla; Repka, Michael X.; Grzybowski, Andrzej

Practicing evidence-based medicine requires constant effort to acquire, assess, and implement new knowledge that improves our care. Since 2013, more than 1000 publications per year have discussed myopia,1 many challenging existing medical beliefs. As in other areas of medicine, ophthalmologists are expected to translate new knowledge into their clinical practice as well as manage their demanding clinical schedu...


Prevalence of anisometropia and its associated factors in school-age children

Hashemi, Hassan; Khabazkhoob, Mehdi; Lança, Carla; Emamian, Mohammad Hassan; Fotouhi, Akbar

Purpose: To determine the prevalence of anisometropia and the associated demographic and biometric risk factors in children. Methods: This cross-sectional study was conducted on the elementary school children of Shahroud, east of Iran, in 2015. All rural students were recruited, while multistage cluster sampling was used to select the students in urban areas. All children underwent optometric examinations inclu...


Visual acuity in high astigmatic eyes in Salta, Argentina

Danza, Rubén D.; Szeps, Abel; Iribarren, Rafael; Lança, Carla

Purpose: To identify factors that affect uncorrected visual acuity (UCVA) in highly astigmatic eyes. Methods: This clinical study was performed at an Ophthalmology Clinic in the Northwest region of Argentina. The study population consisted of all consecutive patients, aged between 10 and 40 years, with bilateral astigmatism higher than 2 dioptres (D) in at least one eye. The protocol included the following test...


Longitudinal changes in crystalline lens thickness and power in children aged 6...

Hashemi, Hassan; Khabazkhoob, Mehdi; Azizi, Elham; Iribarren, Rafael; Lança, Carla; Grzybowski, Andrzej; Rozema, Jos J.; Emamian, Mohammad Hassan

Objectives: To determine the three-year changes in crystalline lens power (LP) and thickness (LT) in children and their associated factors. Methods: Schoolchildren aged 6-12 years living in Shahroud, northeast Iran were examined in 2015 and 2018. The Bennett formula was used to calculate LP. Multiple generalized estimating equations (GEE) analysis was used for data analysis. Results: Among the 8089 examined eye...


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