16 documents found, page 1 of 2
The Assessment of SpondyloArthritis International Society (ASAS) Consensus-Base...
Poddubnyy, Denis; Navarro-Compán, Victoria; TORGUTALP, MURAT; Arends, Suzanne; Aydin, Sibel Zehra; Battista, Simone; Van Den Bosch, FilipPublisher Copyright: © 2025 The Author(s); Objectives: To develop a consensus-based expert definition of difficult-to-manage (D2M) axial spondyloarthritis (axSpA), incorporating treatment-refractory (TR) disease. Methods: A literature review was conducted in 2022 to identify potential definitions for D2M/TR axSpA from prior studies, followed by a 2-round Delphi consensus process conducted in 2022 and 2023 to id...
Change in different classes of chronic back pain suspicious of axial spondyloar...
Bosch, Philipp; Sepriano, Alexandre; Marques, Mary-Lucy; van der Heijde, Désirée; Landewé, Robert; van Lunteren, Miranda; de Bruin, Liese© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.; OBJECTIVES: To follow up four previously identified classes 'pure axial spondyloarthritis' (axSpA) ('axial'), 'axSpA with peripheral signs' ('inflammatory back pain+peripheral'), 'axSpA at risk' and 'no spondyloarthritis' ('no SpA'). They reflect the expert-opinion-free ...
Do fatty lesions explain the effect of inflammation on new syndesmophytes in pa...
Stal, Rosalinde; Ramiro, Sofia; Van Der Heijde, Desirée; Van Gaalen, Floris A.; Baraliakos, Xenofon; Machado, Pedro M.; De Hooge, ManoukFunding Information: This work was supported by Reuma Nederland and Novartis. Publisher Copyright: © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.; Objectives To determine how much of the effect of vertebral corner inflammation on development of syndesmophytes is explained by vertebral corner fat deposition. Methods Pa...
Distinction and prognosis of early arthritis phenotypes
Sepriano, Alexandre; van Dijk, Bastiaan; Ramiro, Sofia; van der Helm-van Mil, Annette; Combe, Bernard; van Schaardenburg, Dirkjan; de Wit, MaartenPublisher Copyright: © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.; OBJECTIVES: The objective of this study is to evaluate whether there are differences in the long-term prognosis across various phenotypes of early arthritis (EA). METHODS: Three EA cohorts (Reade, Etude et Suivi des Polyarthrites Indifférenciées Réce...
Role of vertebral corner inflammation and fat deposition on MRI on syndesmophyt...
Stal, Rosalinde; Baraliakos, Xenofon; van der Heijde, Désirée; van Gaalen, Floris; Ramiro, Sofia; van den Berg, Rosaline; Reijnierse, MoniquePublisher Copyright: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.; OBJECTIVES: To investigate the associations between MRI detected vertebral corner inflammation (VCI) and vertebral corner fat deposition (VCFD) on whole spine low-dose CT scan (ldCT) detected syndesmophyte formation and growth. METHODS: Patients from the Sensitive Imaging in Ankylosing Spondylitis coho...
Inflammation of the sacroiliac joints and spine on MRI predicts structural chan...
Sepriano, Alexandre; Ramiro, Sofia; Landewé, Robert; Moltó, Anna; Claudepierre, Pascal; Wendling, Daniel; Dougados, Maxime; van der Heijde, DésiréeThis article is protected by copyright. All rights reserved.; OBJECTIVE: To test the impact of inflammation on MRI-structural changes occurring in the sacroiliac joints (SIJ) and the spine. METHODS: Patients with early axSpA from the DESIR cohort were included. MRIs of the SIJ (MRI-SIJ) and spine (MRI-spine), obtained at baseline, 2 and 5 years, were scored by 3 central readers. Inflammation and structural dama...
Which imaging outcomes for axSpA are most sensitive to change?
Sepriano, Alexandre; Ramiro, Sofia; van der Heijde, Désirée; Dougados, Maxime; Claudepierre, Pascal; Feydy, Antoine; Reijnierse, MoniqueOBJECTIVE: To compare the sensitivity to change of different imaging scoring methods in patients with early axial spondyloarthritis (axSpA). METHODS: Patients from the DESIR cohort fulfilling the ASAS axSpA criteria were included. Radiographs and MRI of the sacroiliac joints (SIJ) and spine were obtained at baseline, 1, 2 and 5 years. Each image was scored by 2 or 3 readers in 3 separate 'reading-waves'. The ra...
Prevalence and distribution of peripheral musculoskeletal manifestations in spo...
López-Medina, Clementina; Molto, Anna; Sieper, Joachim; Duruöz, Tuncay; Kiltz, Uta; Elzorkany, Bassel; Hajjaj-Hassouni, Najia; Burgos-Vargas, RubenObjectives: To characterise peripheral musculoskeletal involvement in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), across the world. Methods: Cross-sectional study with 24 participating countries. Patients with a diagnosis of axial SpA (axSpA), peripheral SpA (pSpA) or PsA according to their rheumatologist were included. The investigators were asked which diagnosis out of a list of...
TNF inhibitors reduce spinal radiographic progression in patients with radiogra...
Sepriano, Alexandre; Ramiro, Sofia; Wichuk, Stephanie; Chiowchanwisawakit, Praveena; Paschke, Joel; van der Heijde, Désirée; Landewé, RobertThis article is protected by copyright. All rights reserved.; AIM: To investigate whether TNF inhibitors (TNFi) impact spinal radiographic progression in patients with axial spondyloarthritis (axSpA) and whether this is coupled to their effect on inflammation. METHODS: Patients with axSpA fulfilling the modified New York criteria were included in this prospective cohort (ALBERTA FORCAST). Spine radiographs, don...
Identification of clinical phenotypes of peripheral involvement in patients wit...
López-Medina, Clementina; Chevret, Sylvie; Molto, Anna; Sieper, Joachim; Duruöz, Tuncay; Kiltz, Uta; Elzorkany, Bassel; Hajjaj-Hassouni, NajiaObjective To identify clusters of peripheral involvement according to the specific location of peripheral manifestations (ie, arthritis, enthesitis and dactylitis) in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), and to evaluate whether these clusters correspond with the clinical diagnosis of a rheumatologist. Methods Cross-sectional study with 24 participating countries. Consecutiv...