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Hospitalization of symptomatic patients with heart failure and moderate to seve...

Ponikowski, Piotr; Friede, Tim; von Bardeleben, Ralph Stephan; Butler, Javed; Shahzeb Khan, Muhammad; Diek, Monika; Heinrich, Jutta; Geyer, Martin

Background: For patients with functional mitral regurgitation (FMR) and symptomatic heart failure (HF), randomized trials of mitral transcatheter edge-to-edge repair (M-TEER) have produced conflicting results. Objectives: This study sought to assess the impact of M-TEER on hospitalization rates, and explore the effects of M-TEER on patients who did or did not have a history of recent HF hospitalizations before ...


Percutaneous repair of moderate‐to‐severe or severe functional mitral regurgita...

Anker, Stefan D.; Friede, Tim; von Bardeleben, Ralph Stephan; Butler, Javed; Khan, Muhammad Shahzeb; Diek, Monika; Heinrich, Jutta; Geyer, Martin

Aim: The RESHAPE-HF2 trial is designed to assess the efficacy and safety of the MitraClip device system for the treatment of clinically important functional mitral regurgitation (FMR) in patients with heart failure (HF). This report describes the baseline characteristics of patients enrolled in the RESHAPE-HF2 trial compared to those enrolled in the COAPT and MITRA-FR trials. Methods and results: The RESHAPE-HF...


2020 ESC Guidelines for the diagnosis and management of atrial fibrillation dev...

Hindricks, Gerhard; Potpara, Tatjana; Dagres, Nikolaos; Arbelo, Elena; Bax, Jeroen J.; Blomström-Lundqvist, Carina; Boriani, Giuseppe; Castella, Manuel

Atrial fibrillation (AF) poses significant burden to patients, physicians, and healthcare systems globally. Substantial research efforts and resources are being directed towards gaining detailed information about the mechanisms underlying AF, its natural course and effective treatments (see also the ESC Textbook of Cardiovascular Medicine: CardioMed) and new evidence is continuously generated and published. The...


2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein...

Landmesser, Ulf; Chapman, M. John; Stock, Jane K.; Amarenco, Pierre; Belch, Jill J. F.; Borén, Jan; Farnier, Michel; Ference, Brian A.; Gielen, Stephan


New prospects for PCSK9 inhibition?

Landmesser, Ulf; Chapman, M. John; Stock, Jane K.; Amarenco, Pierre; Belch, Jill J. F.; Borén, Jan; Farnier, Michel; Ference, Brian A.; Gielen, Stephan


European Society of Cardiology/European Atherosclerosis Society Task Force cons...

Landmesser, Ulf; Chapman, M. John; Farnier, Michel; Gencer, Baris; Gielen, Stephan; Hovingh, G. Kees; Lüscher, Thomas F.; Sinning, David


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