2 documents found, page 1 of 1
Randomized trials fit for the 21st century. A joint opinion from the European S...
Bowman, Louise; Weidinger, Franz; Albert, Michelle A.; Fry, Edward T. A.; Pinto, Fausto J.; Achenbach, Stephan; Bowman, Louise; Casadei, BarbaraRandomized controlled trials are the cornerstone for reliably evaluating therapeutic strategies. However, during the past 25 years, the rules and regulations governing randomized trials and their interpretation have become increasingly burdensome, and the cost and complexity of trials has become prohibitive. The present model is unsustainable, and the development of potentially effective treatments is often sto...
Potential health and economic impacts of dexamethasone treatment for patients w...
Águas, Ricardo; Mahdi, Adam; Shretta, Rima; Horby, Peter; Landray, Martin; White, Lisa; Arifi, Fatima; Zhumalieva, Chynar; Lubis, Inke N. D.Made available in DSpace on 2021-06-25T10:52:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Li Ka Shing Foundation; Medical Research Council; National Institute for Health Research; Nuffield College, University of Oxford; Dexamethasone can reduce mortality in hospitalised COVID-19 patients needing oxygen and ventilation by 18% and 36%, respectively. Here, we estimate the potential number of li...