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A critique of the second consensus criteria for multiple system atrophy

Stankovic, Iva; Quinn, Niall; Vignatelli, Luca; Antonini, Angelo; Berg, Daniela; Coon, Elizabeth; Cortelli, Pietro; Fanciulli, Alessandra

Multiple system atrophy (MSA) is an adult-onset progressive neurodegenerative disorder that manifests clinically with autonomic failure, parkinsonism, and ataxia in any combination. Oligodendroglial cytoplasmatic inclusions consisting of misfolded α-synuclein are a pathological hallmark of disease. The clinical diagnosis of MSA is typically delayed as a result of incomplete or nonspecific manifestations during ...

Date: 2019   |   Origin: Repositório da Universidade de Lisboa
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