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The anti-tumour effect of spearmint (Mentha spicata) in a HPV-16-transgenic mou...

Jesus, T.M.; Silva-Reis, Rita; Pires, Maria João; Lanzarin, Germano; Félix, Luís; Venâncio, Carlos; Costa, Rui Miguel Gil; Bastos, Margarida M.S.M.

Infection by Human Papillomavirus (HPV) is the main cause of cervical cancer, highlighting the importance of studying compounds that may reduce viral activity and its lesions/symptoms. The aromatic herb spearmint (Mentha spicata) (MS) has proven anti-tumour properties 1. Thus, this study aimed to evaluate the effects of an hydroethanolic extract obtained from spearmint in HPV16-transgenic (HPV+/-) mice. The ext...

Date: 2021   |   Origin: Biblioteca Digital do IPB

Toxicological and anti-tumor effects of a linden extract (Tilia platyphyllos Sc...

Patwal, Tiago; Nascimento-Gonçalves, Elisabete; Macedo, Sara; Borges, Inês; Gama, Adelina; Costa, Rui Miguel Gil; Neuparth, Maria João

Tilia platyphyllos Scop. is a popular broad-leaved tree, native to Central and Southern Europe. Hydroethanolic extracts rich in phenolic compounds obtained from T. platyphyllos Scop. have shown in vitro antioxidant, anti-inflammatory and antitumor properties. The aim of this work was to evaluate the therapeutic properties of a hydroethanolic extract obtained from T. platyphyllos in HPV16-transgenic mice. The an...

Date: 2021   |   Origin: Biblioteca Digital do IPB

The anti-tumour effect of spearmint (Mentha spicata) in a HPV-16-transgenic mou...

Jesus, T.M.; Silva-Reis, Rita; Pires, Maria João; Lanzarin, Germano; Félix, Luís; Venâncio, Carlos; Costa, Rui Miguel Gil; Bastos, Margarida M.S.M.

Infection by Human Papillomavirus (HPV) is the main cause of cervical cancer, highlighting the importance of studying compounds that may reduce viral activity and its lesions/symptoms. The aromatic herb spearmint (Mentha spicata) (MS) has proven anti-tumor properties [1]. Thus, this study aimed to evaluate the effects of an hydroethanolic extract obtained from spearmint in HPV16-transgenic (HPV+/-) mice. The ex...

Date: 2021   |   Origin: Biblioteca Digital do IPB

Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adipo...

Rodrigues, Pedro M.; Ferreira, Tiago; Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Costa, Rui Miguel Gil; Martins, Tânia; Neuparth, Maria João

The production of chestnut (Castanea sativa Miller) is mostly concentrated in Europe. Chestnut is recognized by its high content of antioxidants and phytosterols. This work aimed to evaluate the e ects of dietary chestnut consumption over physiological variables of FVB/n mice. Eighteen FVB/n male 7-month-old mice were randomly divided into three experimental groups (n = 6): 1 (control group) fed a standard diet...

Date: 2020   |   Origin: Biblioteca Digital do IPB

Therapeutic properties of Tilia platyphyllos Scop. in K14HPV16 mice

Ferreira, Tiago; Nascimento-Gonçalves, Elisabete; Gama, Adelina; Costa, Rui Miguel Gil; Neuparth, Maria João; Lanzarin, Germano; Venâncio, Carlos

Tila platyphyllos Scop. is a popular broad-leave tree, native to central and southern Europe

Date: 2020   |   Origin: Biblioteca Digital do IPB

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