8 documents found, page 1 of 1

Molecular Profiling of Axial Spondyloarthritis Patients Reveals an Association ...

Funding Information: D.S. was funded by a fellowship from Fundação para a Ciência e Tecnologia (PTDC/MED535 ONC/28660/2017). This study was funded by Abbvie but the funder had no influence in study design, data analysis, or writing of the submitted document. Publisher Copyright: © 2024 by the authors.; This study aims at identifying molecular biomarkers differentiating responders and non-responders to treatment...

Muscle dysfunction in axial spondylarthritis: the MyoSpA study

Objective We aimed to investigate muscle physical properties, strength, mass, physical performance, and the prevalence of sarcopenia in patients with axial spondylarthritis (axSpA) compared to the healthy controls (HC). Methods We performed a cross-sectional study on 54 participants: 27 patients with axSpA and 27 HC, matched by age, gender, and level of physical activity. Muscle physical properties (stiffness, ...

Lumbar myofascial physical properties in healthy adults

Funding Information: Portuguese Society of Rheumatology grant. Publisher Copyright: © 2021, The Official Journal Of The Portuguese Society Of Rheumatology. All rights reserved.; Objective: The human resting myofascial tone maintains the body tone in a neutral posture, the assessment of this and other muscle physical properties (MPP) is relevant, since, it is altered in many pathological states. Patients and met...

Predictors and causes of first-line biologic agent discontinuation in rheumatoi...

OBJECTIVES: To assess the discontinuation of first-line biological treatment and to evaluate the reasons and predictors thereof in patients with rheumatoid arthritis (RA) from daily clinical practice. METHODS: RA patients registered in the Rheumatic Diseases Portuguese Register (Reuma.pt) starting treatment with biologic DMARDs (bDMARDs) were included in this prospective observational study. The main outcome wa...

The GO-DACT is an investigator-initiated, national, multicentric randomized pla...

The GO-DACT is an investigator-initiated, national, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 2...

The GO-DACT Protocol: a Multicentre, Randomized, Double-Blind, Parallel-Group S...

The GO-DACT is an investigator-initiated, national, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 2...

Do symptoms of depression and anxiety influence treatment response and long-ter...

Do asas, asdas and basdai therapy response evaluation translate the same inform...