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Functional characterization of peripheral blood dendritic cells and monocytes i...

Henriques, A; Inês, L; Carvalheiro, T; Couto, M; Andrade, A; Pedreiro, S; Laranjeiro, P; Morgado, JM; Pais, ML; Pereira da Silva, JA; Paiva, A

With the purpose of contributing to a better knowledge of the APCs functional activity in SLE, we evaluated the distribution and functional ability to produce pro-inflammatory cytokines (TNF-α, IL-1β, IL-6 and IL-12) of peripheral blood (PB) monocytes and DC (tDC), particularly myeloid (mDC) and CD14(-/low)CD16(+) DC subpopulations comparing them with those obtained from healthy individuals. The study was perfo...


Perioperative tumor cell dissemination in patients with primary or metastatic c...

Tralhão, JG; Hoti, E; Serôdio, M; Laranjeiro, P; Paiva, A; Abrantes, AM; Pais, ML; Botelho, MF; Castro e Sousa, F

INTRODUCTION: Although there is general correlation between the TNM stage of colorectal cancer (CRC) and its prognosis, there is often significant variability of tumor behaviour and individual patient outcome, which is unaccounted for by pathologic factors alone. Our aim was to estimate perioperative tumor cell dissemination in patients with primary or CRC liver metastases as a possible factor influencing the o...


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