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Management of hand osteoarthritis: from an US evidence-based medicine guideline...

Fuggle, Nicholas; Bere, Nathalie; Bruyère, Olivier; Rosa, Mário Miguel; Prieto Yerro, María Concepción; Dennison, Elaine; Dincer, Fitnat; Gabay, Cem

Hand osteoarthritis is the most common joint condition and is associated with significant morbidity. It is of paramount importance that patients are thoroughly assessed and examined when complaining of hand stiffness, pain, deformity or disability and that the patient's concerns and expectations are addressed by the healthcare professional. In 2019 the American College of Rheumatology and Arthritis Foundation (...


Multimodal multidisciplinary management of patients with moderate to severe pai...

Veronese, Nicola; Cooper, Cyrus; Bruyère, Olivier; Al-Daghri, Nasser M.; Branco, Jaime; Cavalier, Etienne; Cheleschi, Sara; Rosa, Mário Miguel

Knee osteoarthritis (OA) is one of the most common and disabling medical conditions. In the case of moderate to severe pain, a single intervention may not be sufficient to allay symptoms and improve quality of life. Examples include first-line, background therapy with symptomatic slow-acting drugs for OA (SYSADOAs) or non-steroidal anti-inflammatory drugs (NSAIDs). Therefore, the European Society for Clinical a...


Role of vitamin D supplementation in the management of musculoskeletal diseases...

Chevalley, Thierry; Brandi, Maria Luisa; Cashman, Kevin D.; Cavalier, Etienne; Harvey, Nicholas C.; Maggi, Stefania; Cooper, Cyrus; Al-Daghri, Nasser

Vitamin D is a key component for optimal growth and for calcium-phosphate homeostasis. Skin photosynthesis is the main source of vitamin D. Limited sun exposure and insufficient dietary vitamin D supply justify vitamin D supplementation in certain age groups. In older adults, recommended doses for vitamin D supplementation vary between 200 and 2000 IU/day, to achieve a goal of circulating 25-hydroxyvitamin D (c...


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