2 documents found, page 1 of 1
Differential expression on mitochondrial tryparedoxin peroxidase (mTcTXNPx) in ...
Kohatsu,Andréa A.N.; Silva,Flávia A.J.; Francisco,Acácio I.; Rimoldi,Aline; Silva,Marco T.A.; Vargas,Maria D.; Rosa,João A. da; Cicarelli,Regina M.B.Abstract Resistance to benznidazole in certain strains of Trypanosoma cruzi may be caused by the increased production of enzymes that act on the oxidative metabolism, such as mitochondrial tryparedoxin peroxidase which catalyses the reduction of peroxides. This work presents cytotoxicity assays performed with ferrocenyl diamine hydrochlorides in six different strains of T. cruzi epimastigote forms (Y, Bolivia, ...
Trypanocidal activity of Brazilian plants against epimastigote forms from Y and...
Alves,Renata Tomé; Regasini,Luis Octávio; Funari,Cristiano Soleo; Young,Maria Cláudia Marx; Rimoldi,Aline; Bolzani,Vanderlan da SilvaChagas disease is one of the main public health problems in Latin America. Since the available treatments for this disease are not effective in providing cure, the screening of potential antiprotozoal agents is essential, mainly of those obtained from natural sources. This study aimed to provide an evaluation of the trypanocidal activity of 92 ethanol extracts from species belonging to the families Annonaceae, ...