27 documents found, page 1 of 3
Effects of lapatinib on her2-positive and her2-negative canine mammary carcinom...
Leis-Filho, Antonio Fernando [UNESP]; Lainetti, Patrícia de Faria [UNESP]; Kobayashi, Priscila Emiko [UNESP]; Fonseca-Alves, Carlos Eduardo [UNESP]Made available in DSpace on 2022-04-28T19:41:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01; HER2 is a prognostic and predictive marker widely used in breast cancer. Lapatinib is a tyrosine kinase inhibitor that works by blocking the phosphorylation of the receptor HER2. Its use is related to relatively good results in the treatment of women with HER2+ breast cancer. Thus, this study aimed to v...
Paraneoplastic hypercalcemia secondary to canine mammary tumors
Raposo-Ferreira, Talita Mariana Morata [UNESP]; Varallo, Giovanna Rossi [UNESP]; Calazans, Sabryna Gouveia; Jark, Paulo Cesar [UNESP]Made available in DSpace on 2022-04-28T19:43:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-01-01; Background: Paraneoplastic syndromes are complexes symptom that occur at a distinct site from the primary tumor or its metastasis by the production of hormone by the tissue in which the tumor appears. Paraneoplastic hypercalcemia is associated with an abnormal elevation of serum calcium levels and the m...
Vet-ICD-O-Canine-1, a System for Coding Canine Neoplasms Based on the Human ICD...
Pinello, Katia; Baldassarre, Valeria; Steiger, Katja; Paciello, Orlando; Pires, Isabel; Laufer-Amorim, Renée [UNESP]; Oevermann, AnnaMade available in DSpace on 2022-04-28T19:52:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Fundação para a Ciência e a Tecnologia; Cancer registries are fundamental tools for collecting epidemiological cancer data and developing cancer prevention and control strategies. While cancer registration is common in the human medical field, many attempts to develop animal cancer registries have been ...
Clinical findings of equine leukoencephalomalacia
Albertino, Lukas G. [UNESP]; Dias, Natália M. [UNESP]; Moreira, Juliana J. [UNESP]; Oliveira-Filho, José P. [UNESP]; Takahira, Regina K. [UNESP]Made available in DSpace on 2022-04-29T08:36:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Equine leukoencephalomalacia (LEM) is a disease caused by the ingestion of food, especially corn, contaminated by fumonisin, a Fusarium verticillioides (synonymous with F. moniliforme) metabolite. The clinical signs of brain injuries have an acute onset and rapid evolution. This study aimed to describe ...
P-Glycoprotein and Androgen Receptor Expression Reveals Independence of Canine ...
Cavalca, Alexandre Matheus Baesso [UNESP]; Brandi, Andressa [UNESP]; Fonseca-Alves, Ricardo Henrique; Laufer-Amorim, Renée [UNESP]Made available in DSpace on 2022-04-29T08:38:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Canine prostate cancer (PC) is an aggressive disease, and dogs can be considered comparative models for human PC. In recent years, canine PC has been shown to resemble human castrate-resistant prostate cancer. The influx and efflux of testos...
Female paraurethral prostate gland in bitches
Aguiar, Adriana C. S. [UNESP]; Pinto Rodrigues, Marcela Marcondes [UNESP]; Fonseca-Alves, Carlos Eduardo [UNESP]; Santos, Fernanda C. A.Made available in DSpace on 2022-04-29T07:12:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-12-09; Even though the presence of the female prostate has been reported in many species, including humans, bats and several rodents, it has many anatomical and histological variations. There is still plentiful discussion on the biological function of this organ. Many authors state that paraurethral ducts and ...
Establishment and Characterization of Canine Mammary Gland Carcinoma Cell Lines...
de Faria Lainetti, Patrícia [UNESP]; Brandi, Andressa [UNESP]; Leis Filho, Antonio Fernando [UNESP]; Prado, Maria Carolina Mangini [UNESP]Made available in DSpace on 2021-06-25T10:15:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-27; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Mammary tumors affect intact and elderly female dogs, and almost 50% of these cases are malignant. Cell culture offers a promising preclinical model to study this disease and creates the opportunity to deposit cell lines at a cell bank to al...
Transcriptome of Two Canine Prostate Cancer Cells Treated With Toceranib Phosph...
Kobayashi, Priscila E. [UNESP]; Lainetti, Patrícia F. [UNESP]; Leis-Filho, Antonio F. [UNESP]; Delella, Flávia K. [UNESP]; Carvalho, Marcio [UNESP]Made available in DSpace on 2021-06-25T10:57:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-26; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Canine prostate cancer (PC) presents a poor antitumor response, usually late diagnosis and prognosis. Toceranib phosphate (TP) is a nonspecific inhibitor of receptor tyrosi...
Aggrecan, IL-1β, IL-6, and TNF-α profiles in the Articular Cartilage of Miniatu...
Basso, Roberta M. [UNESP]; Andrade, Danilo G.A. [UNESP]; Alves, Carlos E.F. [UNESP]; Laufer-Amorim, Renée [UNESP]; Borges, Alexandre S. [UNESP]Made available in DSpace on 2021-06-25T11:01:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-01; Dwarfism is a skeletal disorder that causes abnormal growth. In Miniature horses, dwarfism can occur as chondrodysplastic dwarfism, an autosomal recessive disorder associated with five mutations (D1, D2, D3*, D4 and c.6465A > T variant) in the aggrecan (ACAN) gene. The aim of this study was to evaluate ...
Morphological and molecular characterization of proliferative inflammatory atro...
Fernandes, Giovana de Godoy [UNESP]; Pedrina, Bruna [UNESP]; Lainetti, Patrícia de Faria [UNESP]; Kobayashi, Priscila Emiko [UNESP]Made available in DSpace on 2021-06-25T10:27:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-02; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Proliferative inflammatory atrophy (PIA) is an atrophic lesion of the prostate gland that occurs in men and dogs and is associated with a chronic inflammatory infiltrate. In this study, we ret-rospectively reviewed canine prostatic samples f...