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Cutaneous infection by different Alternaria species in a liver transplant recip...

Brás, Susana; Sabino, Raquel; Laureano, André; Simões, Helena; Fernandes, Cândida; Marques-Pinto, Gabriela; Cardoso, Jorge; Veríssimo, Cristina

Fungal invasive infections are rare in general population but are an emergent cause of infection in the immunocompromized population, especially in the solid organ transplant recipients. Herein the authors report a clinical case of a liver transplanted patient suffering a cutaneous co-existent infection with A. alternata as well as A. infectoria. To our knowledge this is the first case of cutaneous concomitant ...


COEXISTENCE OF MORPHEA, VITILIGO AND LATENT AUTOIMMUNE DIABETES OF ADULTHOOD

Laureano, André; Fernandes, Cândida; Cardoso, Jorge

About 30% of adults with morphea have a simultaneous autoimmune disease, which may support the involvement of autoimmunity in the pathogenesis of this fibrosing disorder of the skin and underlying tissues.A 27-year-old man presented with an asymptomatic, erythematous, slightly depressed, indurated oval plaque on the abdominal region that had been present for 1 year. Another dermatological finding was acro-facia...


ERYTHEMA MULTIFORME ASSOCIATED WITH MYCOBACTERIUM TUBERCULOSIS INFECTION

Laureano, André; Fernandes, Cândida; Cardoso, Jorge

Erythema multiforme is an uncommon, immune-mediated disorder that presents with cutaneous or mucosal lesions or both, that occurs as a hypersensitivity reaction in response to infections or drugs. Erythema multiforme is mostly associated with herpes simplex virus. The association with Mycobaterium tuberculosis infection was less frequently described. We present a case of an Erythema multiforme caused by Mycobac...


FAST AND SIMULTANEOUS GROWTH OF MULTIPLE MELANOCYTIC NEVI ASSOCIATED WITH SEMINOMA

Laureano, André; Chaveiro, Alexandra; Correia, Ricardo; Afonso, Ana; Cardoso, Jorge

Potential effects of pregnancy-associated hormones, endogenous and exogenous hormones on melanocytic nevi have been known for years. A 35-year-old man presented with a 6 month history of fast and simultaneous growth of previous, multiple melanocytic nevi located on the trunk, associated with increased levels of beta-human chorionic gonadotropin derived from testicular seminoma. After radical orchiectomy and adj...


DERMOSCOPY IN THE DIAGNOSIS OF COMPOUND TUMORS – A CLINICAL REPORT

Laureano, André; Fernandes, Cândida; Cardoso, Jorge

The coexistence of more than one neoplasm in a single cutaneous specimen is uncommon and has been defined as collision or compound tumor. The authors describe a 66-year-old man who presented with a contiguous seborrheic keratosis and a basal cell carcinoma on the left malar region that had developed in about one year. The case was investigated clinically and focusing on the dermoscopic features and histopatholo...


ZOSTERIFORM MORPHEA

Laureano, André; Pinto, Gabriela Marques; Cardoso, Jorge

A wide variety of pathogenically unrelated skin diseases may follow a zosteriform distribution pattern. Zosteriform morphea is a rare and recently described pattern of presentation of this localized sclerosis of the skin. We report the case of a 26-year old woman with morphea presenting with a zosteriform pattern without a preceding herpes zoster infection. She was treated with topical PUVA for a total of 10 se...


VASCULAR PATTERNS AND MORPHOLOGY IN DERMOSCOPY - PART I. BASIC PRINCIPLES

Laureano, André; Fernandes, Cândida; Cardoso, Jorge

Dermoscopy is a noninvasive, in vivo technique that increases the diagnostic accuracy in both melanocytic and nonmelanocytic skin tumors. In nonpigmented tumors allows the visualization of vascular structures not visible to the naked eye. Part I of this article discusses the dermoscopic evaluation of nonpigmented skin tumors including basic principles of specific morphologic types and architectural arrangement ...


VASCULAR PATTERNS AND MORPHOLOGY IN DERMOSCOPY - PART II. CLINICAL PRACTICE

Laureano, André; Fernandes, Cândida; Cardoso, Jorge

Dermoscopy is a noninvasive, in vivo technique that increases the diagnostic accuracy in both melanocytic and nonmelanocytic skin tumors. In nonpigmented tumors it allows the visualization of vascular structures not visible to the naked eye. Part II of this article discusses clinical applications of dermoscopy in non-pigmented tumoral skin lesions.; A dermatoscopia constitui uma técnica de diagnóstico não-invas...


DISABILITY IN LEPROSY – A RETROSPECTIVE, DESCRIPTIVE AND ANALYTIC STUDY OF 243 ...

Laureano, André; Vieira, Raquel; Medeiros, Sandra; Pacheco, Fernando Assis; Cardoso, Jorge

Introduction: Disability in leprosy may result from peripheral nerve injury. Prevention of disabilities represents one of the major goals of treatment programs.Objectives: Description and comparison of two groups of leprosy patients treated before (“old” patients) and after (“new” patients) multidrug treatment implementation by the World Health Organization, analyzing its potential impact in disability reductio...


POROKERATOSIS OF MIBELLI – A CASE REPORT

Laureano, André; Macias, Vasco Coelho; Pacheco, Fernando Assis

Porokeratosis are the result of a clonal proliferation of keratinocytes. About six clinical variants were des- cribed to date, sharing the histological feature of cornoid lamella in the stratum corneum. The authors report a porokeratosis of Mibelli in a 27-year-old black female appearing in childhood successfully treated with a topical retinoid. Common manifestations of a rare dermatosis are presented with emph...


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