11 documents found, page 1 of 2
Parental infertility and offspring cardiometabolic trajectories: a pooled analy...
Hernáez, Á; Elhakeem, A; Barros, H; Vrijkotte, TGM; Fraser, A; Lawlor, DA; Magnus, MCObjective To assess whether parental infertility is associated with differences in cardiometabolic trajectories in offspring. Design Pooled observational analysis in three prospective cohorts. Setting Three nationwide pregnancy cohorts. Patients A total of 14,609 singletons from the UK Avon Longitudinal Study of Parents and Children, the Portuguese Geraçao 21, and the Amsterdam Born Children and Their Developme...
Prenatal Urban Environment and Blood Pressure Trajectories From Childhood to Ea...
Gonçalves Soares, A; Santos, S; Seyve, E; Nedelec, R; Puhakka, S; Eloranta, A-M; Mikkonen, S; Yuan, WL; Lawlor, DA; Heron, J; Vrijheid, M; Lepeule, JBackground: Prenatal urban environmental exposures have been associated with blood pressure in children. The dynamic of these associations across childhood and later ages is unknown. Objectives: The purpose of this study was to assess associations of prenatal urban environmental exposures with blood pressure trajectories from childhood to early adulthood. Methods: Repeated measures of systolic blood pressure (S...
Long-term cardiometabolic health in people born after assisted reproductive tec...
Elhakeem, A; Taylor, AE; Inskip, HM; Huang, JY; Mansell, T; Rodrigues, C; Asta, F; Blaauwendraad, SM; Haberg, SE; Halliday, J; Harskamp-van Ginkel, MWAims To examine associations of assisted reproductive technology (ART) conception (vs. natural conception: NC) with offspring cardiometabolic health outcomes and whether these differ with age. Methods and results Differences in systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR), lipids, and hyperglycaemic/insulin resistance markers were examined using multiple linear regression models in 14 popu...
Gestational age at birth and body size from infancy through adolescence: An ind...
Vinther, JL; Cadman, T; Avraam, D; Ekstrom, CT; Sorensen, TIA; Elhakeem, A; Santos, AC; de Moira, AP; Heude, B; Iñiguez, C; Pizzi, C; Simons, EBackground Preterm birth is the leading cause of perinatal morbidity and mortality and is associated with adverse developmental and long-term health outcomes, including several cardiometabolic risk factors and outcomes. However, evidence about the association of preterm birth with later body size derives mainly from studies using birth weight as a proxy of prematurity rather than an actual length of gestation. ...
Changes in parental smoking during pregnancy and risks of adverse birth outcome...
Philips, EM; Santos, S; Trasande, L; Aurrekoetxea, JJ; Barros, H; von Berg, A; Bergström, A; Bird, PK; Brescianini, S; Ní Chaoimh, C; Charles, MABackground. Fetal smoke exposure is a common and key avoidable risk factor for birth complications and seems to influence later risk of overweight. It is unclear whether this increased risk is also present if mothers smoke during the first trimester only or reduce the number of cigarettes during pregnancy, or when only fathers smoke. We aimed to assess the associations of parental smoking during pregnancy, spec...
Maternal body mass index, gestational weight gain, and the risk of overweight a...
Voerman, E; Santos, S; Patro Golab, B; Amiano, P; Ballester, F; Barros, H; Bergström, A; Charles, MA; Chatzi, L; Chevrier, C; Chrousos, GPMaternal obesity and excessive gestational weight gain may have persistent effects on offspring fat development. However, it remains unclear whether these effects differ by severity of obesity, and whether these effects are restricted to the extremes of maternal body mass index (BMI) and gestational weight gain. We aimed to assess the separate and combined associations of maternal BMI and gestational weight gai...
Impact of maternal body mass index and gestational weight gain on pregnancy com...
Santos, S; Voerman, E; Amiano, P; Barros, H; Beilin, LJ; Bergström, A; Charles, MA; Chatzi, L; Chevrier, C; Chrousos, GP; Corpeleijn, E; Costa, OObjective To assess the separate and combined associations of maternal pre-pregnancy body mass index (BMI) and gestational weight gain with the risks of pregnancy complications and their population impact. Design Individual participant data meta-analysis of 39 cohorts. Setting Europe, North America, and Oceania. Population 265 270 births. Methods Information on maternal pre-pregnancy BMI, gestational weight gai...
Direct and BMI-mediated effect of birthweight on childhood cardio-metabolic hea...
Fonseca, MJ; Severo, M; Lawlor, DA; Barros, H; Santos, ACBackground Different directions of the association of birthweight with cardio-metabolic health have been found, especially in children, which may be explained by the mediating effect of attained adiposity. We aimed to untangle direct and BMI-mediated associations of birthweight with childhood cardio-metabolic indicators. Methods Children from Generation XXI birth cohort were included (n = 4881). Birthweight was...
Newborn weight change and childhood cardio-metabolic traits - a prospective coh...
Fonseca, MJ; Severo, M; Lawlor, DA; Barros, H; Santos, ACBackground: Newborn weight change (NWC) in the first 4 days represents short-term adaptations to external environment. It may be a key developmental period for future cardio-metabolic health, but this has not been explored. We aimed to determine the associations of NWC with childhood cardio-metabolic traits. Methods: As part of Generation XXI birth cohort, children were recruited in 2005/2006 at all public unit...
Gestational weight gain charts for different body mass index groups for women i...
Santos, S; Eekhout, I; Voerman, E; Gaillard, R; Barros, H; Charles, MA; Chatzi, L; Chevrier, C; Chrousos, GP; Corpeleijn, E; Costet, N; Crozier, SBackgroundGestational weight gain differs according to pre-pregnancy body mass index and is related to the risks of adverse maternal and child health outcomes. Gestational weight gain charts for women in different pre-pregnancy body mass index groups enable identification of women and offspring at risk for adverse health outcomes. We aimed to construct gestational weight gain reference charts for underweight, n...