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Late diagnosis of HIV: An updated consensus definition
Croxford, S; Stengaard, AR; Brännström, J; Combs, L; Dedes, N; Girardi, E; Grabar, S; Kirk, O; Kuchukhidze, G; Lazarus, JV; Noori, T; Pharris, AIntroduction: In recent years, HIV testing frequency has increased, resulting in more people being diagnosed during seroconversion with a temporarily low CD4 count. Using the current consensus definition of late HIV presentation ('presenting for care with a CD4 count < 350 cells/μL or an AIDS-defining event, regardless of CD4 count') these individuals would be incorrectly assigned as being diagnosed late. Metho...
A call to action to reclaim focus on testing and early treatment for HIV, viral...
Stengaard, AR; Raben, D; Leite, RB; Seyler, T; Lazarus, JV; Lambert, J; Collins, B; Attawell, K; Raahauge, A; Rockstroh, JK; Simões, DWe present the outcomes of the HepHIV 2021 Lisbon & virtual conference held on 5-7 May 2021, including a Call to Action addressing policy and practice implications in the field of earlier and integrated testing for HIV, viral hepatitis, STI and TB and in light of lessons learned from the COVID-19 pandemic. Conference presentations showed that combination prevention and integrated testing and care models for mul...
Subnational mapping of HIV incidence and mortality among individuals aged 15–49...
Sartorius, B; VanderHeide, JD; Yang, M; Goosmann, EA; Hon, J; Haeuser, E; Cork, MA; Perkins, S; Jahagirdar, D; Schaeffer, LE; Serfes, AL; LeGrand, KEBackground. High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. Methods. In this modelling study, we devel...
HIV seroprevalence in five key populations in Europe: a systematic literature r...
Stengaard, AR; Combs, L; Supervie, V; Croxford, S; Desai, S; Sullivan, AK; Jakobsen, SF; Santos, Q; Simões, D; Casabona, J; Lazarus, JV; de Wit, JBFBackground: In Europe, HIV disproportionately affects men who have sex with men (MSM), people who inject drugs (PWID), prisoners, sex workers, and transgender people. Epidemiological data are primarily available from national HIV case surveillance systems that rarely capture information on sex work, gender identity or imprisonment. Surveillance of HIV prevalence in key populations often occurs as independent st...
A call to action toward integrated testing and earlier care for viral hepatitis...
Raben, D; Hoekstra, M; Combs, L; Sullivan, AK; Lazarus, JV; Lambert, JS; Simões, D; Streinu-Cercel, A; Rockstroh, JK; Streinu-Cercel, A; Amato-Gauci, AObjectives. The objective of the paper is to present the outcomes of the HepHIV 2019 conference, held in Bucharest under the Romanian EU Presidency and focusing on challenges of timely and integrated testing and care. Methods. The conference programme was put together by the organizing committee. It consisted of invited talks and peer-reviewed abstracts. Results. In all, 65 abstracts from 20 countries were pres...
Global, regional, and national age-sex-specific mortality for 282 causes of dea...
Roth, GA; Abate, D; Abate, KH; Abay, SM; Abbafati, C; Abbasi, N; Abbastabar, H; Abd-Allah, L; Abdela, J; Abdelalim, A; Abdollahpour, I; Abdulkader, RSBackground Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly availa...
Population mobility and the changing epidemics of HIV-2 in Portugal
Carvalho, AC; Valadas, E; França, L; Carvalho, C; Aleixo, MJ; Mendez, J; Marques, R; Sarmento, A; Doroana, M; Antunes, F; Branco, T; Águas, MIntroduction: Portugal is the European country with the highest frequency of HIV-2 infection, which is mainly concentrated in West Africa. The cumulative number of notified HIV-2 infections in Portugal was 1813 by the end of December 2008. To better characterize the dynamics of HIV-2 infection in the country and to obtain data that may be of use in the prevention of the spread of HIV-2, we evaluated a large poo...