Apolipoprotein E (APOE=gene, apoE=protein) is a known factor regulating the inflammatory response that may have regenerative effects during tissue recovery from injury. We investigated whether apoE deficiency reduces the healing effect of alanyl-glutamine (Ala-Gln) treatment, a recognized gut-trophic nutrient, during tissue recovery after 5-FU-induced intestinal mucositis. APOE-knockout (APOE-/-) and wild-type ...
Trypanosoma evansi is the most widespread pathogenic trypanosome, due to its ability to be mechanically transmitted by hematophagous flies. Some studies have shown that T. evansi has a high genetic homology among populations around the world, but they have not described the relationships among infection patterns in the host. In this study, we used molecular techniques to determine the genetic variability of two...