The aim of this study consisted of investigating the influence of bioactive ceramic coatings of silicon substituted hydroxyapatite (Si-HA) over the behaviour of the human osteoblast-like cell (SaOS-2) line. Pulsed laser deposition (PLD) was the selected technique to deposit the coatings over titanium substrates. Diatomaceous earth and SiO2, together with commercial hydroxyapatite were respectively the silicon a...