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Depression in older adults during the COVID -19 pandemic: A systematic review

Fonseca, César; Weidner, Anna; Morgado, Bruno; Lopes, Manuel J.; Moritz, Steffen; Jelinek, Lena; Schneider, Brooke C.; Pinho, Lara G.; Ferreira, Rogério

Background Depression affected 5.7% of people aged 60 years and over prior to the pandemic and has increased by approximately 28%. The aim of this study is to identify and describe factors associated with depressive symptoms, the diagnostic assessment instruments and interventions used to evaluate and treat depression in adults aged 60 years and older since the onset of the COVID-19 pandemic. Methods Four elect...


Pharmacogenomic biomarkers as source of evidence of the effectiveness and safet...

Correia, Catarina; Alcobia, Luciano; Lopes, Manuel J.; Advinha, Ana M.

Objective: The main goal of this work was to identify, describe, characterize, and classify the scientifc evidence regarding the use of pharmacogenomic biomarkers in antidepressant treatment. Methods: The work was developed in two phases: i) a search for pharmacogenomic biomarkers in summaries of antidepressant drugs with marketing authorization in Portugal; and ii) a systematic literature review based on the d...


Prescribing-Assessment Tools for Long-Term Care Pharmacy Practice: Reaching Con...

Gonçalves, João R.; Sleath, Betsy L.; Lopes, Manuel J.; Cavaco, Afonso M

Medicines are the most used health technology in Long-Term Care. The prevalence of potentially inappropriate medicines amongst Long-Term Care patients is high. Pharmacists, assisted by prescribing-assessment tools, can play an important role in optimizing medication use at this level of care. Through a modified RAND/UCLA Appropriateness Method, 13 long-term care and hospital pharmacists assessed as ‘appropriate...


Probing pharmacists' interventions in Long-Term Care: a systematic review

Gonçalves, João Rafael; Ramalhinho, Isabel; Sleath, Betsy L.; Lopes, Manuel J.; Cavaco, Afonso M

Purpose Long-Term Care (LTC) systems have experienced recent developments driven by changes in healthcare and demography (e.g. population ageing). As well, pharmacists are changing from traditional roles to more patient-oriented services. The present study aimed to identify and assess pharmacists’ and/or pharmacy-based interventions in institutional LTC settings, also mapping relevant medications. Methods The r...


Probing pharmacists' interventions in Long-Term Care: a systematic review

Goncalves, Joao R.; Ramalhinho, Isabel; Sleath, Betsy L.; Lopes, Manuel J.; Cavaco, Afonso M.

Key summary pointsAim To investigate pharmacists' interventions and impact at institutional Long-Term Care (LTC) settings, particularly the therapeutic outcomes in elderly populations. Findings LTC pharmacists deliver a comprehensive set of activities, especially in clinical pharmacy (e.g. medication review, deprescribing) and education, addressing elderly populations under LTC and their therapeutic needs. Mess...


Ability assessment of the elders to manage their own medication: a first step f...

Advinha, Ana M.; Nunes, Carla; Lopes, Manuel J.; Oliveira-Martins, Sofia

About 45% of older people are unable to take their medicines as prescribed. Adherence represents a complex behavior that involves both the intention and the ability to take medication. In this way, it is important to distinguish the intention to take medicine and the ability to do so. The daily consumption of medication is a methodical process, marked by routine and that can be affected by several systematic er...


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