O rastreio neonatal tem um papel essencial na deteção precoce da Hiperplasia Congénita das Suprarrenais, numa fase pré-sintomática, permitindo uma institucionalização atempada de tratamento com melhoras no curso clínico do recém-nascido. O marcador utilizado para efeitos de rastreio neonatal, é a 17-α-hidroxiprogesterona (17-OHP), quantificada em cartão de Guthrie por fluoroimunoensaio. No entanto, este marcado...
Medical phantoms are essential to imaging calibration, clinician training, and the validation of therapeutic procedures. However, most ultrasound phantoms prioritize acoustic realism while neglecting the viscoelastic and anisotropic properties of fibrous soft tissues. This gap limits their effectiveness in modeling realistic biomechanical behavior, especially in wave-based diagnostics and therapeutic ultrasound...
Learning objectives: Light-emitting diodes (LEDs) in near-infrared spectrum (810, 850 and 940 nm) enhanced cellular metabolism in a dose-dependent manner. Operation mode, power density, duration and periodicity must be considered in tailoring photobiomodulation (PBM) protocols for specific clinical scenarios. PBM by LEDs enhanced cells´ activity with minimal temperature increase, being a feasible and safe alter...
Preserving biodiversity is a paramount global concern and, in this regard, monitoring urban biodiversity has increasingly taken on a significant role. Citizen science has emerged as a resource for addressing this challenge, offering a cost-effective approach capable of producing extensive data while promoting public engagement. In this work, a Lisbon university campus was used to determine the effectiveness of ...
Hutchinson-Gilford progeria syndrome (HGPS) is a rare and fatal genetic condition that arises from a single nucleotide alteration in the LMNA gene, leading to the production of a defective lamin A protein known as progerin. The accumulation of progerin accelerates the onset of a dramatic premature aging phenotype in children with HGPS, characterized by low body weight, lipodystrophy, metabolic dysfunction, skin...
Through the compilation of the verdicts issued by the Court of Final Appeal of the Macao Special Administrative Region, this article investigates, from an introductory study, the need and feasibility of building a Portuguese Chinese parallel corpus in the legal area, as well as the development of strategies to be applied as a methodological resource in computer aided translation tools, with the aim of seeking w...
Meningoencephalitis is a syndrome of multiple etiologies associated with important morbidity and mortality. It may be caused by various infectious agents (viruses, bacteria, parasites and fungi). Establishing the etiology of meningoencephalitis is crucial for early and specific treatment. Molecular assays such as the multiplex polymerase chain reaction (PCR) offer an alternative in diagnosing central nervous sy...
Translation process research has focused on alphabetic scripts in post-editing and translation tasks from the second language (L2) into the mother tongue (L1). This chapter approaches translation and post-editing tasks involving Chinese, which has a logographic script, in combination with Portuguese. The aim is to compare task type (translation and post-editing) and directionality (L2-L1 and L1-L2) focusing on ...
Abstract Background Neuromuscular isokinetic screening as a pre-season test may identify players at risk of injury or undertrained players. Objective Identify, assess and describe unilateral and bilateral knee muscular deficits in elite football players at pre-season screening. Design Retrospective cohort. Setting Elite football divisions. Patients (or Participants) Of 99 eligible male elite footballers, older ...