28 documents found, page 1 of 3

Pathologies and clinical cases in biochemistry

Biochemical changes during the human lifespan

Sjögren's syndrome and its impact in the oral cavity

Sjögren's syndrome is an autoimmune disease that affects salivary gland tissue. Patients can show different degrees of phenotype that can vary from mild to severe systemic symptoms. So far, the etiopathogenesis of this condition is still not fully unraveled but it is believed that genetic and environmental factors are involved. The purpose is to understand the role of genetics on the appearance of the Sjögren's...

Oral and craniofacial manifestations of mucopolysaccharidoses

Mucopolysaccharidoses (MPS) are a group of inherited metabolic disorders caused by the deficiency of lysosomal enzymes necessary for the degradation of glycosaminoglycans (GAGs). Non-degraded GAGs accumulate inside the lysosomes and compromise cell function in different tissues and organs. This accumulation causes progressive and multisystemic damage, leading to a wide spectrum of clinical manifestations, inclu...

C-Reactive protein and neurodegenerative diseases

Systemic lupus erythematosus and implications for the oral cavity

Systemic Lupus Erythematosus affects several people around the world and because it is characterized as a chronic inflammatory disease of multifactorial origin, and with systemic impairment, great attention must be paid from diagnosis to treatment in order to optimize the entire follow-up of the patient. The dental doctor plays an important role in the diagnosis of the condition and must be attentive to the ear...

Cornelia de Lange Syndrome and orofacial implications

Background and objective: Cornelia de Lange syndrome is a rare disease with a very wide and genetically heterogeneous phenotypic variability that affects multiple organs and systems. This work consists of a narrative review on Cornelia de Lange syndrome, specifically addressing its orofacial manifestations and the impact of these changes on dentistry. Methods: For the bibliographic search, the following databas...

Genetic and environmental factors involved in the development of oral malformat...

Among the most common malformations observed in the oral cavity are cleft lip/palate and malocclusions, being this last one considered by the World Health Organization, the third public health problem. Malocclusions include the anterior open bite, a change in the vertical plane, that can be of two types: dental anterior open bite and skeletal anterior open bite. Cleft lip and cleft palate are the most common co...

Biochemical mechanisms of the effect of environmental factors (diet, fluorine, ...

Nowadays, oral diseases are prevalent chronic diseases present in worldwide population. Dental caries results from a complex interaction between acid-producing bacteria, fermentable carbohydrates and host factors, including teeth and saliva. Risk factors for caries development include physical, biological, environmental, behavioral factors such as high numbers of cariogenic bacteria, inadequate salivary flow, p...

A qualidade como vetor da revisão curricular: o caso do curso de licenciatura e...