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Host immune genetic variations influence the risk of developing acute myeloid l...

Sánchez-Maldonado, J. M.; Campa, D.; Springer, J.; Badiola, J.; Niazi, Y.; Moñiz-Díez, A.; Hernández-Mohedo, F.; González-Sierra, P.; Ter Horst, R.

© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party ...


Polymorphisms in host immunity modulating genes and risk of invasive aspergillo...

Lupiañez, C. B.; Canet, L. M.; Carvalho, Agostinho Albérico Rodrigues de; Alcazar-Fuolie, L.; Springer, J.; Lacknerg, M.; Segura-Catena, J.; Comino, A.

Recent studies suggest that immune-modulating single nucleotide polymorphisms (SNPs) influence the risk of developing cancer-related infections. Here, we evaluated whether 36 SNPs within 14 immune-related genes are associated with the risk of Invasive Aspergillosis (IA) and whether genotyping of these variants might improve disease risk prediction. We conducted a case-control association study of 781 immunocomp...


Polymorphisms in xenobiotic transporters ABCB1, ABCG2, ABCC2, ABCC1, ABCC3 and ...

Martino, A.; Campa, D.; Buda, G.; Sainz, J.; GarcIa Sanz, R.; Jamroziak, K.; Reis, R. M.; Weinhold, N.; Jurado, M.; Rıos, R.; Szemraj-Rogucka, Zofia

Multiple myeloma (MM) is a hematological neoplasm that arises from a single clone of malignant plasma cells in the bone marrow. In Europe, 4.6/100 000 males and 3.2/100 000 females every year develop MM, with a median age at diagnosis around 60 years.; Polish Ministry of Science and Higher Education (Lodz, Poland) - NN40217833; Fondo de Investigaciones Sanitarias (Madrid, Spain) - PI081051; Consejería de Salud ...


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