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Strenuous Acute Exercise Induces Slow and Fast Twitch-Dependent NADPH Oxidase E...

Alves, Juliana Osório; Pereira, Leonardo Matta; Monteiro, Igor Cabral Coutinho do Rêgo; Santos, Luiz Henrique Pontes dos; Ferraz, Alex Soares Marreiros

The enzymatic complex Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase (NOx) may be the principal source of reactive oxygen species (ROS). The NOX2 and NOX4 isoforms are tissue-dependent and are differentially expressed in slow-twitch fibers (type I fibers) and fast-twitch fibers (type II fibers) of skeletal muscle, making them different markers of ROS metabolism induced by physical exercise. The aim...

Date: 2021   |   Origin: Oasisbr

A Compendium of Physical Exercise-related Human Genes: An'OMIC Scale Analysi

Pacheco, Christina; Felipe, Stela Mirla da Silva; Soares, Milca Magalhães Dias de Carvalho; Alves, Juliana Osório; Soares, Paula Matias

: Regular exercise is an exogenous factor of gene regulation with numerous health benefits. The study aimed to evaluate human genes linked to physical exercise in an ‘omic scale, addressing biological questions to the generated database. Three literature databases were searched with the terms ‘exercise’, ‘fitness’, ‘physical activity’, ‘genetics’ and ‘gene expression’. For additional references, papers were scr...

Date: 2021   |   Origin: Oasisbr

Expression of myo-inositol cotransporters in the sciatic nerve and dorsal root ...

Farias, V. X.; Uchoa, P.N.; Aquino, Camila P.; Britto, L.R.G.; Fonteles, Manasses Claudino; Leal-Cardoso, José Henrique; Silva-Alves, Kerly Shamyra da

The transport of myo-inositol is the main mechanism for the maintenance of its high intracellular levels. We aimed to measure the mRNA and protein levels of myo-inositol cotransporters in the sciatic nerve (SN) and dorsal root ganglia (DRG) during experimental diabetes. Streptozotocin-induced (STZ; 4, 8, and 12 weeks; 65 mg/kg; ip) diabetic rats (DB) and age-matched euglycemic (E) rats were used for the analysi...

Date: 2019   |   Origin: Oasisbr

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