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Application of human biomonitoring data to support policy development, raise aw...

Ubong, Dorothy; Stewart, Lorraine; Sepai, Ovnair; Knudsen, Lisbeth E.; Berman, Tamar; Reynders, Hans; Van Campenhout, Karen; Katsonouri, Andromachi

Most countries have acknowledged the importance of assessing and quantifying their population’s internal exposure from chemicals in air, water, soil, food and other consumer products due to the potential health and economic impact. Human biomonitoring (HBM) is a valuable tool which can be used to quantify such exposures and effects. Results from HBM studies can also contribute to improving public health by prov...


A case study on occupational exposure to Chromium (VI), Nickel, PAH mixtures an...

Silva, Maria João; Louro, Henriqueta; Viegas, Susana; Gomes, Bruno Costa; Santonen, Tiina; Kortenkamp, Andreas; Lebret, Erik

Background: In several industries, e.g., aircrafts maintenance, workers are co-exposed to a range of hazardous substances, including hexavalent chromium [Cr (VI)], nickel (Ni) and polycyclic aromatic hydrocarbons (PAHs). Each of these compounds can cause serious health effects, including lung cancer. However, the association between exposure and health outcome has not been analysed from a mixture perspective, i...


Plan for development of case studies - Deliverable Report AD 15.1 WP 15 - Mixtu...

Kortemkamp, Andreas; Mengelers, Marcel; Vinggaard, Anne Marie; Silva, Maria João; Slamay, Remy; Vermeulen, Roel; Vlaanderen, Jelle; Ottenbros, Ilse

This deliverable describes the activities in task 15.3 leading up to the development of cases studies for mixture health effects and outlines the proposed case studies. The proposed case studies are: · Developmental neurotoxicity beyond polybrominated diphenylethers · Heavy metals and nephrotoxicity · Anti-androgenic chemicals and male reproductive health · Chromium (VI), nickel and polycyclic aromatic hydrocar...


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