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Brucellosis in Portugal: A systematic review and meta-analysis of animal and hu...

Lopes, Ricardo; Lima de Carvalho, Hugo; Leclerc Duarte, Elsa; Coelho, Ana Claudia; Cardoso, Luis Lucas; Garces, Andreia

Brucellosis remains one of the most widespread zoonoses globally, yet its true burden in Portugal remains insufficiently characterised1,2,3,4. This study presents the first nationwide systematic review and meta-analysis of Brucella spp. infections across both animal and human populations in Portugal, following PRISMA and MOOSE guidelines. A total of 871 studies were screened, yielding 62 eligible reports publis...


What do we know about Cryptococcus spp. in Portugal?

Lopes, Ricardo; Barros, Gonçalo; Garces, Andreia; Cardoso, Luis; Silva, Vanessa; Lima de Carvalho, Hugo; Leclerc Duarte, Elsa; Coelho, Ana Cláudia

Cryptococcosis is an environmentally acquired mycosis primarily caused by the Cryptococcus neoformans and C. gattii species complexes. These encapsulated yeasts infect humans and multiple animal hosts. In veterinary medicine their importance has gained recognition in recent decades, and affected animals can act as sentinels of environmental exposure within a One Health/Planetary Health framework (Figure 1). In ...


First description of antifungal susceptibility of yeast-like fungi in dermal le...

Lopes, Ricardo; Garcês, Andreia; Leclerc Duarte, Elsa; Cardoso, Luis; Coelho, Ana Cláudia; Brilhante Simoes, Paula

Yeast infections, particularly those caused by species of the genera Malassezia and Candida, are important contributors to otitis and dermatitis in dogs. This study investigates the prevalence and antifungal resistance of various yeast-like fungi isolated from canine dermal lesions in Portugal. Between 2018 and 2023, samples from dogs with clinically suspected yeast infections were collected and analysed using ...


Mapping Multi-Host TB Risk: The Central Role of Wild Boar and Red Deer in Envir...

Ferreira, Eduardo; Cunha, Monica; Leclerc Duarte, Elsa; Mira, António; Santos, Sara M

Animal tuberculosis (TB) persists in multi-host communities Transmission occurs via shared contaminated environments; Integration of host ecology and environmental data is crucial. Indirect interactions more frequent → wet season • Natural resource availability increased wildlife-cattle interactions. • 49% environmental samples positive for MTBC DNA. Main contamination predictor: terrain slope 26.5% area = high...


Antimicrobial prophylaxis in companion animal surgery: A scoping review for Eur...

Sorensen, Tina M; Correia Dias, Margarida; Leclerc Duarte, Elsa; Marques, Catia; Allerton, Fergus; Jessen, Lisa R; Weese, Scott

Surgical antimicrobial prophylaxis (SAP) is widely used to reduce the risk of surgical site infections (SSI), but there is uncertainty as to what the proportion of SSI reduction is. Therefore, it is difficult for surgeons to properly weigh the costs, risks and benefits for individual patients when deciding on the use of SAP, making it challenging to promote antimicrobial stewardship in primary practice settings...


“Biomarkers in a One Health perspective: current knowledge of their ability to ...

Lavrador, Catarina; Vilhena, Manuela; Abreu de Assunção, Ricardo; Soromenho de Alvito, Paula; Leclerc Duarte, Elsa

Biomarkers are nowadays essential tools to be one step ahead for fighting disease, enabling an enhanced focus on disease prevention and on the probability of its occurrence. Research in a multidisciplinary approach has been an important step towards the repeated discovery of new biomarkers. Biomarkers are defined as biochemical measurable indicators of the presence of disease or as indicators for monitoring dis...


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