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Germ line gain of function with SOS1 mutation in hereditary gingival fibromatosis

Jang, Shyh-Ing; Lee, Eun-Jin; Hart, P. Suzanne; Ramaswami, Mukundhan; Pallos, Débora; Hart, Thomas Charles

Made available in DSpace on 2019-09-12T16:53:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2007; Office of Intramural Research (OIR) NIH HHS; Mutation of human SOS1 is responsible for hereditary gingival fibromatosis type 1, a benign overgrowth condition of the gingiva. Here, we investigated molecular mechanisms responsible for the increased rate of cell proliferation in gingival fibroblasts caused by mu...

Date: 2019   |   Origin: Oasisbr
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