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Interleukin-6 gene -174G>C and -636G>C promoter polymorphisms and prostate canc...
Magalhães, J. F.; Cortinhas, A. J.; Albuquerque, C. M.; Baptista, C. S.; Ribeiro, R.; Viegas, Carlos A.; Matos, Augusto; Machado, João; Pires, Maria A.Prostate cancer (PCa) is one of the most commonly diagnosed internal malignancies affecting men. Due to the important roles of IL-6 in different physiological and pathophysiological processes,IL-6polymorphisms may modulate PCa risk.IL-6−174 G>C (rs 1800795, also designated −236 G>C) and −636 G>C (rs 1800796, also designated −572 G>C) promoter polymorphisms have been implicated in PCa susceptibility, albeit stil...
Date: 2013
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Origin: RepositóriUM - Universidade do Minho