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Síndrome mielodisplásica variante hipoplásica: análise estatística no serviço d...
Martins, Henrique Girão; Barroso, Karine Sampaio Nunes; Leitão, João Paulo de Vasconcelos; Araujo, Beatriz Stela Gomes de Souza PitombeiraObjectives: To analyze, in patients with myelodysplastic syndrome (MDS) hypoplastic variant of the Bone Marrow Transplant service, the response to the transplant and perform a comparison with data from the MDS Latin American database. Methodology: Analytical, cross-sectional and retrospective study by analyzing medical records, including all patients diagnosed with MDS undergoing bone marrow transplantation, ev...
Protocolo de tratamento do mieloma múltiplo: serviço de hematologia Hospital Un...
Sousa, Jacqueline Holanda de; Silva, Herivaldo Ferreira da; Gurgel, Livia Andrade; Leitão, João Paulo de VasconcelosMultiple Myeloma (MM) is a hematological neoplasm characterized by bone marrow infiltration by clonal (malignant) plasma cells and the production of a monoclonal protein (MP). The disease remains incurable, although in recent years, with the advent of new treatments, progressive improvements in rates and duration of remission have been observed, resulting in a significant survival increment for affected patient...
Wernicke’s encephalopathy in a patient with non- Hodgkin’s lymphoma post-Autolo...
Leitão, João Paulo de Vasconcelos; Lemes, Romélia Pinheiro Gonçalves; Barbosa, Maritza Cavalcante; Araújo, Beatriz Stela Gomes de Souza PitombeiraWernick’s Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely considered in patients submitted to this procedure. Considering that, the manuscript reports the clinical characteristics and the possible factors that predisposed t...
Efeitos do tratamento com l-alanil-glutamina sobre o estresse oxidativo em rato...
Leitão, João Paulo de VasconcelosThe effect of L-alanil-glutamine was tested in a situation of oxidative stress induced by torsion of the spermatic cord. Eighty four male young Wistar rats were distributed randomly in 6 groups: Saline group 1h (GSa1) and Ala-Gln Group 1h (GAg1), animals of these groups were submitted to 1 hour of ischemia and 6 hours of reperfusion and were treated 30 minutes before the torsion, by intravenous way, with saline...