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Estimating glomerular filtration rate in acute coronary syndromes: Different eq...

Almeida, I; Caetano, F; Barra, S; Madeira, M; Mota, P; Leitão-Marques, A

AIMS: Renal dysfunction is a powerful predictor of adverse outcomes in patients hospitalized for acute coronary syndrome. Three new glomerular filtration rate (GFR) estimating equations recently emerged, based on serum creatinine (CKD-EPIcreat), serum cystatin C (CKD-EPIcyst) or a combination of both (CKD-EPIcreat/cyst), and they are currently recommended to confirm the presence of renal dysfunction. Our aim wa...


Phenotypic expression in hypertrophic cardiomyopathy and late gadolinium enhanc...

Caetano, F; Botelho, A; Trigo, J; Silva, J; Almeida, I; Venâncio, M; Pais, J; Sanches, C; Leitão-Marques, A

INTRODUCTION AND AIM: The prognostic value of late gadolinium enhancement (LGE) for risk stratification of hypertrophic cardiomyopathy (HCM) patients is the subject of disagreement. We set out to examine the association between clinical and morphological variables, risk factors for sudden cardiac death and LGE in HCM patients. METHODS: From a population of 78 patients with HCM, we studied 53 who underwent cardi...


Can cardiac computed tomography predict cardiovascular events in asymptomatic t...

Faustino, A; Providência, R; Mota, P; Barra, S; Silva, J; Fernandes, A; Catarino, R; Basso, S; Costa, M; Leitão-Marques, A

BACKGROUND: Doubts remain about atherosclerotic disease and risk stratification of asymptomatic type-2 diabetic patients (T2DP). This study aims to evaluate the usefulness of calcium score (CS) and coronary computed tomography (CT) angiography (CTA) to predict fatal and non fatal cardiovascular events (CVEV) in T2DP. METHODS: Eighty-five consecutive T2DP undergoing CT (Phillips Brilliance, 16-slice) with CS and...


Non-Hodgkin lymphoma as an uncommon cause of acute heart failure

Caetano, F; Mota, P; Trigo, J; Basso, S; Araújo, LF; Leitão-Marques, A


Emerging and under-recognized Chagas cardiomyopathy in non-endemic countries

Cortez, J; Providência, R; Ramos, E; Valente, C; Seixas, J; Meruje, M; Leitão-Marques, A; Vieira, A

Due to recent population emigration movements, an epidemic of Chagas disease is currently menacing most developed countries. The authors report the case of a 53-year-old Brazilian woman living in Europe for the last 10 years who developed heart failure symptoms, having a previous symptomatic sinus node disease with a pacemaker implant at age of 40 years. The diagnosis was based on serology and myocardial biopsy...


Overview of resistant hypertension: A glimpse of the cardiologist's current sta...

Paiva, L; Cachulo, MC; Providência, R; Barra, S; Dinis, P; Leitão-Marques, A

Hypertension is a major risk factor for cardiovascular disease, resulting in increased incidence of cerebrovascular events, ischaemic heart disease, heart failure, and renal impairment. Thus, it is one of the most important preventable causes of premature morbidity and mortality. Despite current knowledge on the management of hypertension and the availability of several effective antihypertensive medications, u...


Cerclage na prevenção do parto pré-termo: revisão de 13 casos

Castro, MG; Santos-Silva, A; Leitão-Marques, A; Mimoso, G; Matos, L

O parto pré-termo é o principal responsável pela morbilidade e mortalidade perinatal em países industrializados. Entre as diferentes causas, destaca-se um conjunto de situações caracterizado pela dilatação indolor do colo uterino com prolapso das membranas no canal cervical (funnelling), que ocorre mais frequentemente durante o segundo trimestre da gestação, dando origem a abortos tardios ou partos pré-termo mu...


Enfarte agudo do miocárdio no puerpério: a propósito de um caso clínico

Providência, R; Mota, P; Rosa-Pais, J; Leitão-Marques, A

Acute myocardial infarction is a rare event in the puerperium that can have life-threatening consequences if not diagnosed early. Spontaneous coronary artery dissection is the most frequent causative mechanism in the period immediately after labor. This article reports the case of a 38-year-old woman with acute myocardial infarction due to spontaneous coronary artery dissection on the 7th day after delivery. Th...


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