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Polypharmacological strategies for infectious bacteria

Leita, MM; Gonçalves, ASC; Borges, F; Simoes, M; Anabela Borges

Polypharmacological approaches have significant potential for the treatment of various complex diseases, including infectious bacteria-related diseases. Actually, multitargeting agents can achieve better therapeutic effects and overcome the drawbacks of monotherapy. Although multidrug multitarget strategies have demonstrated the ability to inactivate infectious bacteria, several challenges have been pointed out...


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