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Height Benefit of GnRH Agonists After Age 8 in a Portuguese Cohort of Central P...

Castro, C; Espada, F; Leite, AL; Antunes, A; Robalo, B; Amaral, D; Galo, E; Castro, S; Ferreira, S; Limbert, C

Objective: Idiopathic central precocious puberty (iCPP) is common in paediatric endocrinology. Gonadotropin-releasing hormone agonists (GnRHa) are safe, but the effect on final height and the ideal timing for treatment remains controversial. This study aims to assess the effectiveness of GnRHa on growth outcomes in girls with iCPP treated before and after the age of 8 years old. Design and patients: This retros...


Do GnRH Agonists Really Increase Body Weight Gain? Evaluation of a Multicentric...

Leite, AL; Galo, E; Antunes, A; Robalo, B; Amaral, D; Espada, F; Castro, S; Simões Dias, S; Limbert, C

Introduction: There are several concerns associated with gonadotropin-releasing hormone agonist (GnRHa) treatment for central precocious puberty (CPP), such as obesity and changes in body mass index (BMI). We aimed to investigate whether any anthropometric differences exist and if they persist over time. Methods: We conducted an observational study of Portuguese children (both sexes) diagnosed with CPP between ...


Caso dermatológico: Kerion celsi

Monteiro, MI; Leite, AL; Rodrigues, J; Costa, M; Oliveira, T; Rocha, C

Kerion Celsi is an inflammatory presentation of tinea capitis, caused by a hypersensitivity reaction mediated by T lymphocytes of the dermatophyte in hair follicles. The early clinical recognition avoids invasive procedures. Hyperleukocytosis/ leukemoid reactions are hematologic reactional responses that may result. The most frequently involved agents are Trichophyton verrucosum, Trichophyton mentagrophytes, Mi...


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