62 documents found, page 1 of 7
Functional properties and safety considerations of zinc oxide nanoparticles und...
Mendes, Ana Rita; Granadeiro, Carlos M.; Leite, Andreia; Geiss, Otmar; Bianchi, Ivana; Ponti, Jessica; Mehn, Dora; Pereira, Eulália; Teixeira, PaulaZinc oxide nanoparticles (ZnO NPs) exhibit diverse morphologies and sizes, influencing their functional properties. However, the relationship between their morphology and behavior under varying conditions remains poorly understood. This study provides novel insights by linking ZnO NPs shape to generation of reactive oxygen species (ROS), and to antimicrobial efficacy under varying temperatures. ROS generation w...
High burden of hospital morbidity and mortality due to Chagas disease in Bahia ...
García, Gabriela Soledad Márdero; Leite, Andreia; de Souza, Eliana Amorim; Ferreira, Anderson Fuentes; de Sousa, Andrea Silvestre; Luiz, Ronir RaggioChagas disease (CD) is a chronic condition associated with high morbidity and mortality in endemic regions of Brazil, particularly in the state of Bahia. The clinical-epidemiologic analysis of hospital admissions is strategic due to limited data on chronic CD infections and the general lack of access to diagnosis and treatment. This study examines sociodemographic and clinical-epidemiological patterns of hospit...
Characteristics and incidence trends of adults hospitalized with community-acqu...
Carneiro, Joana; Teixeira, Rita; Leite, Andreia; Lahuerta, Maria; Catusse, Julie; Ali, Mohammad; Lopes, SílviaCommunity-acquired pneumonia (CAP) is a major cause of hospitalization that leads to substantial morbidity, mortality, and costs. Evaluating CAP trends over time is important to understand patterns and the impact of public health interventions. This study aims to describe the characteristics and trends in the incidence of adults hospitalized with CAP in Portugal between 2010 and 2018. In this study, we included...
Patient and family engagement interventions for enhancing patient safety in the...
Seyfulayeva, Ayshe; Fonte, Bianca Ferreira; Alho, Ana Margarida; Shaikh, Anum; Nunes, Ana Beatriz; Casaca, Pedro Gonçalves Carvalho; Leite, AndreiaBackground: Surgical procedures present intricate challenges within healthcare delivery, often associated with higher risks of adverse events compared with non-surgical contexts. Patient and family engagement (PFE) throughout the perioperative journey is a possibility to enhance care quality, safety and patient-centredness. However, literature addressing PFE across the entirety of the perioperative journey rema...
Is a tiered restrictions system an effective intervention for COVID-19 control?...
Moniz, Marta; Soares, Patricia; Nunes, Baltazar; Leite, AndreiaBackground: In November 2020, similar to other European countries, Portugal implemented a tiered restrictions system to control the COVID-19 pandemic. We aimed to compare the COVID-19 growth rate across tiers to assess the effect of a tiered restrictions system in Portugal, using models with different times between tiers assessment. Our hypothesis was that being in a higher tier brings a faster deceleration in ...
Sickle cell trait in São Tomé e Príncipe: a population-based prevalence study i...
Queiroz, Guilherme; Monteiro, Celdidy; Manco, Licínio; Relvas, Luís; Trovoada, Maria de Jesus; Leite, Andreia; Bento, CelesteBackground Sickle Cell Disorder is Africa’s most prevalent genetic disease. Yet, it remains a neglected condition, with high mortality under-five, and a lack of population-based studies in the region. This is the first of its kind in São Tomé e Príncipe, aiming to estimate the prevalence of sickle cell trait and other haemoglobin variants in women of reproductive age and its associated factors. Methods: We cond...
Moving towards a core measures set for patient safety in perioperative care: An...
Dinis-Teixeira, J.P.; Nunes, Ana Beatriz; Leite, Andreia; Schäfer, Willemijn L.A.; Valli, Claudia; Martínez-Nicolas, Ismael; Seyfulayeva, AysheA Core Measures Set (CMS) is an agreed standardized group of measures that should be assessed and reported in research for a specific condition or clinical area. This study undertook the development of a CMS for Patient Safety through a two-round, web-based Delphi consensus approach, in the context of the "Improving quality and patient SAFEty in surgical care through STandardisation and harmonization of periope...
Long COVID is not the same for everyone: a hierarchical cluster analysis of Lon...
Moniz, Marta; Ruivinho, Carolina; Goes, Ana Rita; Soares, Patricia; Leite, AndreiaBackground: Identifying symptom clusters in Long COVID is necessary for developing effective therapies for this diverse condition and improving the quality of life of those affected by this heterogeneous condition. In this study, we aimed to identify and compare symptom clusters at 9 and 12 months after a SARS-CoV-2 positive test and describe each cluster regarding factors at infection. Methods: This is a cross...
Individual risk factors associated with SARS-CoV-2 infection during Alpha varia...
Moniz, Marta; Pereira, Sofia; Soares, Patricia; Aguiar, Pedro; Donato, Helena; Leite, AndreiaObjectives: This study aimed to systematically appraise risk factors associated with SARS-CoV-2 infection in high-income countries during the period of predominance of the Alpha variant (January 2020 to April 2021). Methods: Four electronic databases were used to search observational studies. Literature search, study screening, data extraction and quality assessment were conducted by two authors independently. ...
Optimizing antimicrobial efficacy: investigating the impact of zinc oxide nanop...
Mendes, Ana Rita; Granadeiro, Carlos M.; Leite, Andreia; Pereira, Eulália; Teixeira, Paula; Poças, FátimaZinc oxide nanoparticles (ZnO NPs) have been investigated due to their distinct properties, variety of structures and sizes, and mainly for their antimicrobial activity. They have received a positive safety evaluation from the European Food Safety Authority (EFSA) for packaging applications as transparent ultraviolet (UV) light absorbers based on the absence of significant migration of zinc oxide in particulate...