65 documents found, page 1 of 7
Functional properties and safety considerations of zinc oxide nanoparticles und...
Mendes, Ana Rita; Granadeiro, Carlos M.; Leite, Andreia; Geiss, Otmar; Bianchi, Ivana; Ponti, Jessica; Mehn, Dora; Pereira, Eulália; Teixeira, PaulaZinc oxide nanoparticles (ZnO NPs) exhibit diverse morphologies and sizes, influencing their functional properties. However, the relationship between their morphology and behavior under varying conditions remains poorly understood. This study provides novel insights by linking ZnO NPs shape to generation of reactive oxygen species (ROS), and to antimicrobial efficacy under varying temperatures. ROS generation w...
High burden of hospital morbidity and mortality due to Chagas disease in Bahia ...
García, Gabriela Soledad Márdero; Leite, Andreia; de Souza, Eliana Amorim; Ferreira, Anderson Fuentes; de Sousa, Andrea Silvestre; Luiz, Ronir RaggioChagas disease (CD) is a chronic condition associated with high morbidity and mortality in endemic regions of Brazil, particularly in the state of Bahia. The clinical-epidemiologic analysis of hospital admissions is strategic due to limited data on chronic CD infections and the general lack of access to diagnosis and treatment. This study examines sociodemographic and clinical-epidemiological patterns of hospit...
Characteristics and incidence trends of adults hospitalized with community-acqu...
Carneiro, Joana; Teixeira, Rita; Leite, Andreia; Lahuerta, Maria; Catusse, Julie; Ali, Mohammad; Lopes, SílviaCommunity-acquired pneumonia (CAP) is a major cause of hospitalization that leads to substantial morbidity, mortality, and costs. Evaluating CAP trends over time is important to understand patterns and the impact of public health interventions. This study aims to describe the characteristics and trends in the incidence of adults hospitalized with CAP in Portugal between 2010 and 2018. In this study, we included...
Patient and family engagement interventions for enhancing patient safety in the...
Seyfulayeva, Ayshe; Fonte, Bianca Ferreira; Alho, Ana Margarida; Shaikh, Anum; Nunes, Ana Beatriz; Casaca, Pedro Gonçalves Carvalho; Leite, AndreiaBackground: Surgical procedures present intricate challenges within healthcare delivery, often associated with higher risks of adverse events compared with non-surgical contexts. Patient and family engagement (PFE) throughout the perioperative journey is a possibility to enhance care quality, safety and patient-centredness. However, literature addressing PFE across the entirety of the perioperative journey rema...
Use of quasi-experimental studies to evaluate causal effects of public health i...
Leite, Andreia; Kislaya, Irina; Machado, Ausenda; Aguiar, P.; Nunes, B.; Dias, Carlos MatiasBackground: Quasi-experimental designs are a valid option to assess causal effects of public health interventions when randomized studies are unfeasible, but not widely used in Portugal. We identified and reviewed characteristics of studies employing quasi-experimental designs to evaluate causal effects of public health interventions in Portugal. Methods: PubMed, Scopus, Web of Science and CINHAL were searched,...
Risk of stroke or myocardial infarction hospitalisation following hospitalisati...
Carneiro, Joana; Leite, Andreia; Lahuerta, Maria; Catusse, Julie; Ali, Mohammad; Teixeira, Rita; Lopes, SílviaObjectives: We aimed to assess the risk of cardiovascular hospitalisations (stroke or myocardial infarction (MI)) following a community-acquired pneumonia (CAP) hospitalisation in a large Portuguese administrative dataset. Design: Self-controlled case series study. Setting: We used hospitalisation data from National Health Service hospitals across Portugal between 2010 and 2018. Participants: Adults hospitalise...
Long-term cardiovascular events in individuals hospitalised with COVID-19: a re...
Soares, Patricia; Ruivinho, Carolina; Silva, Joana; Lobão, Maria João; Santos, Lelita; Paixão, Joana; Ramalho, Ana Rita; Henriques, AdrianaBackground: Post-COVID condition encompasses a spectrum of persistent or emerging symptoms affecting multiple organ systems, including a heightened risk of cardiovascular complications. Despite growing recognition of this phenomenon, there remains a lack of comprehensive data regarding the incidence and risk factors associated with cardiovascular events during the post-acute phase in patients previously hospita...
Is a tiered restrictions system an effective intervention for COVID-19 control?...
Moniz, Marta; Soares, Patricia; Nunes, Baltazar; Leite, AndreiaBackground: In November 2020, similar to other European countries, Portugal implemented a tiered restrictions system to control the COVID-19 pandemic. We aimed to compare the COVID-19 growth rate across tiers to assess the effect of a tiered restrictions system in Portugal, using models with different times between tiers assessment. Our hypothesis was that being in a higher tier brings a faster deceleration in ...
Sickle cell trait in São Tomé e Príncipe: a population-based prevalence study i...
Queiroz, Guilherme; Monteiro, Celdidy; Manco, Licínio; Relvas, Luís; Trovoada, Maria de Jesus; Leite, Andreia; Bento, CelesteBackground Sickle Cell Disorder is Africa’s most prevalent genetic disease. Yet, it remains a neglected condition, with high mortality under-five, and a lack of population-based studies in the region. This is the first of its kind in São Tomé e Príncipe, aiming to estimate the prevalence of sickle cell trait and other haemoglobin variants in women of reproductive age and its associated factors. Methods: We cond...
Moving towards a core measures set for patient safety in perioperative care: An...
Dinis-Teixeira, J.P.; Nunes, Ana Beatriz; Leite, Andreia; Schäfer, Willemijn L.A.; Valli, Claudia; Martínez-Nicolas, Ismael; Seyfulayeva, AysheA Core Measures Set (CMS) is an agreed standardized group of measures that should be assessed and reported in research for a specific condition or clinical area. This study undertook the development of a CMS for Patient Safety through a two-round, web-based Delphi consensus approach, in the context of the "Improving quality and patient SAFEty in surgical care through STandardisation and harmonization of periope...