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Characterization of the genetic diversity of Mycobacterium tuberculosis in São ...

Mendes, Natália H; Melo, Fernando A.F.; Santos, Adolfo C.B.; Pandolfi, José R.C.; Almeida, Elisabete A.; Cardoso, Rosilene F.; Berghs, Henri

Background: Tuberculosis is a major health problem in São Paulo, Brazil, which is the most populous and one of the most cosmopolitan cities in South America. To characterize the genetic diversity of Mycobacterium tuberculosis in the population of this city, the genotyping techniques of spoligotyping and MIRU were applied to 93 isolates collected in two consecutive years from 93 different tuberculosis patients r...


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