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Avaliação da Vanillosmopsis arborea Baker e (-)-α-bisabolol frente a parâmetros...

Leite, Gerlânia de Oliveira

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES; Vanillosmopsis arborea Baker belongs to the Asteraceae family and has a recognized economic value due to its anti-inflammatory properties, derived from sesquiterpene (-)-α-bisabolol (BISA), which is present in high concentrations in the essential oil of its wood (OEVA). BISA is used in a wide variety of dermatological products. Some studies su...

Date: 2018   |   Origin: Oasisbr
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Topical antinociceptive effect of vanillosmopsis arborea baker on acute corneal...

Leite, Laura Hévila Inocêncio; Leite, Gerlânia de Oliveira; Coutinho, Thales Silva; Sousa, Severino Denício Gonçalves de; Sampaio, Renata Souza

This study aimed to assess the possible topical antinociceptive activity of Vanillosmopsis arborea Baker essential oil (EOVA) and to clarify the underlying mechanism, using the acute model of chemical (eye wiping) nociception in mice. EOVA (25 to 200mg/kg; p.o. and topical) evidenced significant antinociception against chemogenic pain in the test model of formalin-induced neuroinflammatory pain. Local applicati...

Date: 2014   |   Origin: Oasisbr
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