5 documents found, page 1 of 1
Farnesol against Coccidioides posadasii : its effect on growth, ergosterol
Brilhante, Raimunda Sâmia Nogueira; Lima, Rita Amanda Chaves de; Caetano, Erica Pacheco; Leite, João Jaime GiffoniCoccidioidomycosis is a systemic mycosis caused by the dimorphic fungi Coccidioides spp. The treatment for chronic and/or disseminated coccidioidomycosis can be prolonged and complicated. Therefore, the search for new drugs is necessary. Farnesol is a precursor in the sterol biosynthesis pathway that has been shown to present antifungal activity. Thus, the objective of this study was to evaluate the in vitro an...
Effect of farnesol on growth, ergosterol biosynthesis, and cell permeability in...
Caetano, Erica Pacheco; Brilhante, Raimunda Sâmia Nogueira; Lima, Rita Amanda Chaves de; Leite, João Jaime GiffoniCoccidioidomycosis is a systemic mycosis caused by the dimorphic fungi Coccidioides spp. The treatment for chronic and/or disseminated coccidioidomycosis can be prolonged and complicated. Therefore, the search for new drugs is necessary. Farnesol is a precursor in the sterol biosynthesis pathway that has been shown to present antifungal activity. Thus, the objective of this study was to evaluate the in vitro an...
Yeasts from Macrobrachium amazonicum : a focus on antifungal susceptibilityand ...
Brilhante, Raimunda Sâmia Nogueira; Paiva, Manoel de Araújo Neto; Sampaio, Célia M.S.; Teixeira, Carlos Eduardo CordeiroIn the present study, it was sought to compare yeast microbiota of wild and captive Macrobrachium amazonicum and evaluate the antifungal susceptibility and production of virulence factors by the recovered isolates of Candida spp. Additionally, cultivation water was monitored for the presence of fungi. Overall, 26 yeast isolates belonging to three genera and seven species were obtained, out of which 24 were Cand...
Sesquiterpene farnesol contributes to Increased susceptibility to beta-Lactams ...
Brilhante, Raimunda Sâmia Nogueira; Valente, L. G. A.; Rocha, Marcos Fábio Gadelha; Bandeira, Tereza de Jesus Pinheiro GomesThis study aimed to evaluate the in vitro combination of farnesol and -lactams against Burkholderia pseudomallei . A total of 12 -lactamase-positive strains were tested according to CLSI standards. All strains were inhibited by farnesol, with MICs ranging from 75 to 150 M. The combination of this compound with -lactams resulted in statistically significant -lactam MIC reduc- tion ( P < 0.05). This study provide...
Caracterização fenotípica, perfil de sensibilidade antifúngica e estocagem de m...
Leite, João Jaime GiffoniThe genus Malassezia enclose lipophylic and lipid-dependent yeast that after many changes in its taxonomic classification, comprises in the atuality 13 species, including M. pachydermatis, M. furfur, M. sympodialis, M. globosa, M. obtusa, M. restricta, M. slooffiae, M. dermatis, M. japonica, M. yamatoensis, M. nana, M. equine, and M. caprae. These yeasts are associated to several diseases including, such as pit...