11 documents found, page 1 of 2
A functional polymorphism in IL-36β modulates macrophage antifungal effector fu...
Gonçalves, Samuel M.; Leite, L.; de Vasconcelos, P.; Pereira, I.; Dewi, I. M. W.; Mercier, T.; Aerts, R.; Ligeiro, D.; Mendes, F.; Freitas, F.Background: Genetic predisposition plays a major role in the development of invasive pulmonary aspergillosis (IPA). The risk and course of IPA vary significantly among patients, yet continuously new genetic mechanisms that influence individual antifungal immune responses are being discovered. While genetic variability in interleukin (IL)-1 family cytokines is recognized as an important cause of disease suscepti...
Ustekinumab in Real-Life Practice: Experience in 116 Patients with Moderate-To-...
Raposo, I.; Bettencourt, A.; Leite, L.; Selores, M.; T, TorresUstekinumab is a monoclonal antibody directed against the p40 subunit common to both IL-12 and IL-23 cytokines. Although the evidence of ustekinumab efficacy and safety in clinical trials is extensively recognized, data on its use in clinical practice is limited. Our objective is to report on the real-life experience of two Portuguese dermatology departments with ustekinumab in patients with moderate to severe ...
Rheumatic hand's clinical, functional and imagiological correlations following ...
Figueiredo, S.; Pereira, A.; Silva, M.; Leite, L.; Costa, G.; Silva, C.Objective: Evaluation of rheumatoid hand-associated metacarpophalangeal joint silicone arthroplasty most often relies on functional scores alone. This study aimed to understand the correlation between perceived and observed function, strength, and alignment. Methods: Cross-sectional study including all 11 women (15 hands) submitted to second to fifth metacarpophalangeal joint arthroplasty due to rheumatoid arth...
Portuguese Position Paper on the Use of Biosimilars in Psoriasis
Torres, T.; Ferreira, A.; Ferreira, P.; Henriques, M.; Leite, L.; Magina, S.; Marques-Pinto, G.; Oliveira, H.; Sousa-Basto, A.; Tavares-Bello, R.
Ecological quality assessment of transitional waters based on fish assemblages:...
Cabral, H.N.; Fonseca, V.F.; Gamito, R.; Gonçalves, C.I.; Costa, J.L.; Erzini, K.; Gonçalves, J.; Martins, J.; Leite, L.; Andrade, J.P.; Ramos, S.The assessment of water quality has changed markedly worldwide over the last years, especially in Europe due to the implementation of the Water Framework Directive. Fish was considered a key-element in this context and several fish-based multi-metric indices have been proposed. In this study, we propose a multimetric index, the Estuarine Fish Assessment Index (EFAI), developed for Portuguese estuaries, designed...
From a traditionally open access fishery to modern restrictions: Portuguese ang...
Veiga, Pedro; Pita, C.; Leite, L.; Ribeiro, J.; Ditton, R. B.; Gonçalves, J. M. S.; Erzini, KarimSaltwater recreational fishing (SRF) in Portugal was for a long time an open-access activity, without restrictions of any kind. Restrictions to control the recreational harvest were first implemented in 2006 and were highly criticized by the angler community, for being highly restrictive and lacking scientific support. The present study aimed to obtain socio-economic data on the recreational shore anglers and g...
Ecological quality assessment of transitional waters based on fish assemblages ...
Cabral, H. N.; Fonseca, V. F.; Gamito, R.; Gonçalves, C. I.; Costa, J. L.; Erzini, Karim; Gonçalves, Jorge Manuel Santos; Martins, J.; Leite, L.The assessment of water quality has changed markedly worldwide over the last years, especially in Europe due to the implementation of the Water Framework Directive. Fish was considered a key-element in this context and several fish-based multi-metric indices have been proposed. In this study, we propose a multi-metric index, the Estuarine Fish Assessment Index (EFAI), developed for Portuguese estuaries, designe...
Ecological quality assessment of transitional waters based on fish assemblages ...
Cabral, H. N.; Fonseca, V. F.; Gamito, R.; Gonçalves, C. I.; Costa, J. L.; Erzini, Karim; Gonçalves, J. M. S.; Martins, J.; Leite, L.The assessment of water quality has changed markedly worldwide over the last years, especially in Europe due to the implementation of the Water Framework Directive. Fish was considered a key-element in this context and several fish-based multi-metric indices have been proposed. In this study, we propose a multimetric index, the Estuarine Fish Assessment Index (EFAI), developed for Portuguese estuaries, designed...
Robustness of the Estuarine Fish Assessment Index (EFAI) regarding water body d...
Gonçalves, C. I.; Pasquaud, S.; Gamito, R.; Fonseca, V. F.; Costa, J. L.; Erzini, Karim; Gonçalves, Jorge Manuel Santos; Martins, J.; Leite, L.According to the Water Framework Directive (WFD) transitional waters should be differentiated according to type and, in some cases, divided into different water bodies. This raises a dilemma in trying to define parts of a continuum. In the sequence of WFD several indices have been proposed including the Estuarine Fish Assessment Index, which can be applied taking an estuary as a whole (EFAI - without water bodi...
Caso hematológico: hemorragia tardia pós adeno-amigdalectomia
Salgado, M.; Costa, E.; Campos, F.; Leite, L.; Freitas, I.; Barbot, J.The authors present the clinical case of a six years old child followed by Pediatric Hematology because of anemia detected after a late hemorrhage following adenotonsillectomy, debating the differential diagnosis and management.