5 documents found, page 1 of 1
Anti-Mycobacterium tuberculosis and Cytotoxicity Activities of Ruthenium(II)/ B...
Lima,Benedicto A. V.; Corrêa,Rodrigo S.; Graminha,Angelica E.; Kuznetsov,Aleksey; Ellena,Javier; Pavan,Fernando R.; Leite,Clarice Q. F.The [Ru(Spym)(bipy)(P–P)]PF6, [Spym = pyrimidine-2-thiolate anion; P–P = 1,2-bis(diphenylphosphino)ethane, 1,3-bis(diphenylphosphino)propane and 1,1'-bis(diphenylphosphino)ferrocene] complexes were synthesized and characterized by spectroscopic, electrochemical and elemental analysis, and by X-ray crystallography. The minimal inhibitory concentration (MIC) of the compounds against Mycobacterium tuberculosis and...
Cobalt(III) complexes with thiosemicarbazones as potential anti-Mycobacterium t...
Oliveira,Carolina G.; Maia,Pedro Ivo da S.; Miyata,Marcelo; Pavan,Fernando R.; Leite,Clarice Q. F.; Almeida,Eduardo Tonon de; Deflon,Victor M.CoIII complexes derived from 2-acetylpyridine N(4)-R thiosemicarbazone (Hatc-R, R = alkyl, aryl) have been characterized by elemental analysis, FTIR, UV-Visible and ¹H NMR spectroscopies, cyclic voltammetry (CV), conductimetry measurements and single crystal X-ray diffractometry. The results obtained are consistent with the oxidation of the CoII center to CoIII upon coordination of the monoanionic N,N,S-trident...
Paepalanthus spp: antimycobacterial activity of extracts, methoxylated flavonoi...
Moreira,Raquel R. D.; Martins,Gilmarcio Z.; Pietro,Rosemeire C. L. R.; Sato,Daisy N.; Pavan,Fernando R.; Leite,Sergio R.A.; Vilegas,WagnerPaepalanthus spp., Eriocaulaceae, are native plants from Brazil known as "sempre-vivas" (everlasting flowers). In this work, we evaluated the potential anti-mycobacterial activity of two methoxylated flavonoids (flavonoid 7-methylquercetagetin and 7-methylquercetagetin-4'-O-β-D-glucopyranoside) isolated and identified from P. latipes and the naphthopyranone fractions from P. bromeliodes ethanolic extracts. The ...
Anti-Mycobacterium tuberculosis activity of fungus Phomopsis stipata
Prince,Karina Andrade de; Sordi,Renata; Pavan,Fernando Rogério; Santos,Adolfo Carlos Barreto; Araujo,Angela R.; Leite,Sergio R.A.; Leite,Clarice Q. F.Our purpose was to determine the anti-Mycobacterium tuberculosis activity of the metabolites produced by the endophitic fungus Phomopsis stipata (Lib.) B. Sutton, (Diaporthaceae), cultivated in different media. The antimycobacterial activity was assessed through the Resazurin Microtiter Assay (REMA) and the cytotoxicity test performed on macrophage cell line. The extracts derived from fungi grown on Corn Medium...
Palladium(II) complexes with thiosemicarbazones: syntheses, characterization an...
Maia,Pedro I. da S.; Graminha,Angélica; Pavan,Fernando R.; Leite,Clarice Q. F.; Batista,Alzir A.; Back,Davi F.; Lang,Ernesto S.; Ellena,JavierThree PdII complexes were prepared from N(4)-substituted thiosemicarbazones: [Pd(aptsc)(PPh3)](NO3)H2O, 1, [Pd(apmtsc)(PPh3)](NO3), 2, and [Pd(apptsc)(PPh3)](NO3)H2O, 3, where PPh3 = triphenylphosphine; Haptsc = 2-acetylpyridine-thiosemicarbazone; Hapmtsc = 2-acetylpyridine-N(4)-methyl-thiosemicarbazone and Happtsc = 2-acetylpyridine-N(4)-phenyl-thiosemicarbazone. All complexes were characterized by elemental...