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Paepalanthus spp: antimycobacterial activity of extracts, methoxylated flavonoi...

Moreira,Raquel R. D.; Martins,Gilmarcio Z.; Pietro,Rosemeire C. L. R.; Sato,Daisy N.; Pavan,Fernando R.; Leite,Sergio R.A.; Vilegas,Wagner

Paepalanthus spp., Eriocaulaceae, are native plants from Brazil known as "sempre-vivas" (everlasting flowers). In this work, we evaluated the potential anti-mycobacterial activity of two methoxylated flavonoids (flavonoid 7-methylquercetagetin and 7-methylquercetagetin-4'-O-β-D-glucopyranoside) isolated and identified from P. latipes and the naphthopyranone fractions from P. bromeliodes ethanolic extracts. The ...

Date: 2013   |   Origin: Oasisbr

Anti-Mycobacterium tuberculosis activity of fungus Phomopsis stipata

Prince,Karina Andrade de; Sordi,Renata; Pavan,Fernando Rogério; Santos,Adolfo Carlos Barreto; Araujo,Angela R.; Leite,Sergio R.A.; Leite,Clarice Q. F.

Our purpose was to determine the anti-Mycobacterium tuberculosis activity of the metabolites produced by the endophitic fungus Phomopsis stipata (Lib.) B. Sutton, (Diaporthaceae), cultivated in different media. The antimycobacterial activity was assessed through the Resazurin Microtiter Assay (REMA) and the cytotoxicity test performed on macrophage cell line. The extracts derived from fungi grown on Corn Medium...

Date: 2012   |   Origin: Oasisbr

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