28 documents found, page 1 of 3

Borreliosis as a cause of myocarditis in pediatric age

Introduction: Lyme borreliosis (LB) is a zoonosis with worldwide distribution, mainly in the northern hemisphere countries with predominantly cutaneous, articular, cardiac and neuro-psychiatric manifestations. The greater variety of genospecies that cause disease in Europe and the complex laboratory confirmation contribute to the disease underdiagnose in Portugal. Case description: A 17-year-old boy resident in...

Effect of commercial emerging nonthermal technologies on food products: microbi...

Human leucocyte antigens class II allele and haplotype association with Type 1 ...

This study confirms for Madeira Island (Portugal) population the Type 1 Diabetes (T1D) susceptible and protective Human leucocyte antigens (HLA) markers previously reported in other populations and adds some local specificities. Among the strongest T1D HLA associations, stands out, as susceptible, the alleles DRB1*04:05 (OR = 7.3), DQB1*03:02 (OR = 6.1) and DQA1*03:03 (OR = 4.5), as well as the haplotypes DRB1*...

HLA-DQA1 and HLA-DQB1 allele diversity and its extended haplotypes in Madeira I...

This study shows, for the first time, high-resolution allele frequencies of HLA-DQA1 loci in Madeira Island (Portugal) and allows us to better understand and refine present knowledge on DQB1 variation, with the identification of several alleles not previously reported in this population. Estimates on haplotype profile, involving HLA-A, HLA-B, HLADRB1, HLA-DQA1 and HLA-DQB1, are also reported.

Antibiotic-loaded Sr-doped porous calcium phosphate granules as multifunctional...

Multifunctional porous calcium phosphate granules intended as osseous fillers and drug carriers were designed. Strontium- and magnesium-co-substituted biphasic hydroxyapatite (HA)/beta-tricalcium phosphate powders (TCP) with compositions close to the mineral part of human bone [(Ca+Sr+Mg)/P=1.62] were prepared by precipitation, heat treated and deagglomerated, and characterized by XRD and SEM. Highly concentrat...

Antibiotic-loaded Sr-doped porous calcium phosphate granules as multifunctional...

Multifunctional porous calcium phosphate granules intended as osseous fillers and drug carriers were designed. Strontium- and magnesium- co-substituted biphasic hydroxyapatite (HA)/β-tricalcium phosphate powders (TCP) with compositions close to the mineral part of human bone [(Ca+Sr+Mg)/P=1.62] were prepared by precipitation, heat treated and deagglomerated, and characterized by XRD and SEM. Highly concentrated...

Avaliação Nutricional de Crianças com Doença Celíaca Seguidas na Consulta de Ga...

A doença celíaca (DC) tardiamente diagnosticada pode levar a um quadro de desnutrição grave. O seu tratamento limita-se à instituição de dieta isenta de glúten, aspecto nem sempre respeitado com rigor pelos doentes. O presente trabalho tem como principal objectivo avaliar o cumprimento da dieta e a sua repercussão nutricional em doentes celíacos. Foram incluídas 72 crianças que frequentam a consulta externa de ...

Addition of spent yeast extract on the production of cooked ham- Compositional ...

The Neber approach to 2-(Tetrazol-5-yl)-2H-Azirines

The synthesis of 2-(tetrazol-5-yl)-2H azirines is reported for the first time. Using the Neber approach, β-ketoxime-1H-tetrazoles were converted into the target 2Hazirines bearing phenyl, furan-2-yl, thiophen-2-yl, or pyrrol-2-yl substituents at C-3. It was demonstrated that the alkaloidmediated Neber reaction allows the asymmetric synthesis of 2-(tetrazol-5-yl)-2H-azirines.

Functionalization of dipyrromethanes via hetero-Diels–Alder reaction with azo- ...

5,50-Diethyl- and 5-phenyldipyrromethanes participate in cycloadditions with azo- and nitrosoalkenes giving dipyrromethanes with side chains containing open chain oximes and hydrazones. By controlling reaction stoichiometry it is possible to get mono or 1,9-disubstituted derivatives. The reported methodology gave access to a range of dipyrromethanes with good structural features for various applications. It was...