11 documents found, page 1 of 2
Physical Activity, Exercise, and Sports in Individuals with Skeletal Dysplasia:...
Jacinto, Miguel; Matos, Rui; Alves, Inês; Lemos, Carolina; Monteiro, Diogo; Morouço, Pedro; Antunes, RaulThere is a lack of knowledge about the practice of physical activity, exercise, and sports in people with skeletal dysplasia (SD). This study aimed to characterize the physical fitness of people with SD; investigate the benefits of physical activity, exercise, or sports programs for people with SD; identify the adapted physical activities that can be prescribed to individuals with SD; and identify the most comm...
Physical Activity, Exercise, and Sports in Individuals with Skeletal Dysplasia:...
Jacinto, Miguel; Matos, Rui; Alves, Inês; Lemos, Carolina; Monteiro, Diogo; Morouço, Pedro; Antunes, Raulhere is a lack of knowledge about the practice of physical activity, exercise, and sports in people with skeletal dysplasia (SD). This study aimed to characterize the physical fitness of people with SD; investigate the benefits of physical activity, exercise, or sports programs for people with SD; identify the adapted physical activities that can be prescribed to individuals with SD; and identify the most commo...
CD44v6 high membranous expression is a predictive marker of therapy response in...
Almeida, Gabriela M; Pereira, Carla; Park, Ji-Hyeon; Lemos, Carolina; Campelos, Sofia; Gullo, Irene; Martins, Diana; Gonçalves, Gilza; Leitão, Dina© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).; In gastric cancer (GC), biomarkers that define prognosis and predict treatment response remain scarce. We hypothesized that the extent of CD44v6 membranous tumor expression ...
Female preponderance in genetic generalized epilepsies
Videira, Gonçalo; Gabriel, Denis; Freitas, Joel; Samões, Raquel; Chorão, Rui; Lopes, João; Ramalheira, João; Ramalheira, João E.P.; Lemos, CarolinaIntroduction: Epilepsy is more prevalent in men but Genetic Generalized Epilepsies (GGE) seem to be more common in women. A predominant maternal inheritance has been previously described in GGE. Our objective was to determine sex and inheritance patterns in a GGE population compared to mesial temporal lobe epilepsy with hippocampal sclerosis (MTLEHS). Methods: We performed a prospective observational study incl...
Discrimination and Access Barriers to the National Health Service Perceived by ...
Rodrigues, João; Lemos, Carolina; Figueiredo, ZéliaIntroduction: Trans people, who need specific medical, surgical and psychological healthcare due to their condition, are confronted with discrimination, prejudice and stigma thus limiting their access to health services. The present study aims to assess barriers in trans health in three distinct public services (emergency, primary care and surgery). Material and Methods: A non‑controlled cross‑sectional study w...
Long-Term Follow-Up of Advanced Liver Disease after Sustained Virological Respo...
Pereira Guedes, Tiago; Fragoso, Pedro; Lemos, Carolina; Garrido, Mónica; Silva, Joana; Falcão, Daniela; Maia, Luís; Moreira, TeresaBackground: Direct-acting antivirals (DAA) have revolutionized hepatitis C treatment, with high sustained virological response (SVR) rates reported, even in historically difficult-to-treat groups. SVR is associated with a decreased risk of hepatocellular carcinoma (HCC), need for transplantation, and overall and liver-related mortality. Data from real-life cohorts on the medium- to long-term outcomes of patient...
Twenty Years of a Pre-Symptomatic Testing Protocol for Late-Onset Neurological ...
Paneque, Milena; Félix, Joana; Mendes, Álvaro; Lemos, Carolina; Lêdo, Susana; Silva, João; Sequeiros, JorgeIntroduction: The national protocol of genetic counselling and pre-symptomatic testing for late-onset neurological diseases began in Portugal in 1995. Initially, it was accessible only to adults at-risk for Machado-Joseph disease, but was later extended to other hereditary ataxias, to Huntington’s disease and to familial amyloid polyneuropathy caused by Val30Met mutation at the transthyretin gene. The aim of th...
Proposal of a Portuguese Tool for Quality Assessment of Genetic Counselling: a ...
Paneque, Milena; Costa, Catarina; Lemos, Carolina; Alves-Ferreira, Miguel; Sequeiros, Jorge; Lemos, Marina SerraIntroduction: The lack of tools for quality assessment of genetic counselling is recognized in national and international studies. The correlation of quality of healthcare practice with greater satisfaction of patients and affected families is also well established. The present study describes the development and validation of the first Portuguese scale for quality assessment of genetic counselling practice. It...
PRODUÇÃO DE INTERNAÇÕES HOSPITALARES, NO SISTEMA ÚNICO DE SAÚDE, NA REGIÃO DE R...
Lemos, Carolina; Chaves, Lucieli Dias PedreschiEste estudo objetivou caracterizar a dinâmica da produção física e financeira de internações hospitalares, em 25municípios da região de Ribeirão Preto, São Paulo, Departamento Regional de Saúde XIII (DRS-XIII). Pesquisadescritivo-exploratória, cuja coleta de dados foi a pesquisa documental. A população de estudo constituiu-se pelasinternações, processadas pelo Sistema de Informações Hospitalares (SIH) do Sistem...
The C677T polymorphism in MTHFR is not associated with migraine in Portugal
Ferro, Anabela; Castro, Maria-José; Lemos, Carolina; Santos, Mónica; Sousa, Alda; Pereira-Monteiro, José; Sequeiros, Jorge; Maciel, P.Migraine is a debilitating disorder affecting a large proportion of the population. The effect of methylenetetrahydrofolate reductase (GeneID: 4524) polymorphisms in migraine etiology and development has been a theme of great interest. Several populations were evaluated with contradictory results. In this case-control study, we investigated the effect of the C677T polymorphism in MTHFR, as a genetic risk factor...