7 documents found, page 1 of 1
The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondr...
Lemos, V; de Oliveira, RM; Naia, L; Szegö, É; Ramos, E; Pinho, S; Magro, F; Cavadas, C; Rego, AC; Outeiro, TF; Gomes, PInsulin resistance is a major predictor of the development of metabolic disorders. Sirtuins (SIRTs) have emerged as potential targets that can be manipulated to counteract age-related diseases, including type 2 diabetes. SIRT2 has been recently shown to exert important metabolic effects, but whether SIRT2 regulates insulin sensitivity in hepatocytes is currently unknown. The aim of this study is to investigate ...
Correlação entre Espessura Macular e Camada de Fibras Nervosas Peripapilar no G...
Cabugueira, A; Vicente, A; Lemos, V; Anjos, R; Rosa, R; Flores, R; Gomes, T; Reina, MIntrodução: Os autores pretendem analisar a espessura macular e a camada de fibras nervosas peripapilar (CFN) em doentes com glaucoma inicial e com o diagnóstico de hipertensão ocular (HTO). Também propõem um modelo de correspondência da espessura macular de uma dada região do hemisfério superior com a CFN temporal superior (TS) e do hemisfério inferior com a CFN temporal inferior (TI) no glaucoma inicial. Mate...
The Impact of Multifocal Intraocular Lens in Retinal Imaging with Optical Coher...
Dias-Santos, A; Costa, L; Lemos, V; Anjos, R; Vicente, A; Ferreira, J; Cunha, JPMultifocal intraocular lenses (MF IOLs) have concentric optical zones with different dioptric power, enabling patients to have good visual acuity at multiple focal points. However, several optical limitations have been attributed to this particular design. The purpose of this study is to access the effect of MF IOLs design on the accuracy of retinal optical coherence tomography (OCT). Cross-sectional study cond...
Intraocular Pressure in Eyes Receiving Intravitreal Antivascular Endothelial Gr...
Lemos, V; Cabugueira, A; Noronha, M; Abegão Pinto, L; Reina, M; Branco, J; Gomes, TPURPOSE: The aim of the this study was to determine the effect of intravitreal antivascular endothelial growth factor injections on intraocular pressure (IOP) and identify possible risk factors for the development of increased IOP. MATERIALS AND METHODS: This prospective study included a total of 106 eyes receiving intravitreal injection of bevacizumab as treatment for macular edema or active choroidal neovascu...
Anterior Segment Optical Coherence Tomography Imaging of Filtering Blebs after ...
Vieira, L; Noronha, M; Lemos, V; Reina, M; Gomes, TPurpose: To describe the technique of deep sclerectomy with the new Esnoper-Clip® implant, the clinical outcome and the anatomic characteristics of filtering blebs, using anterior segment optical coherence tomography (AS-OCT). Methods: A prospective case-series study was conducted in five eyes (5 patients) with open angle glaucoma. The fornixbased deep sclerectomy with Esnoper-Clip® implant was done by the same...
Vision Loss and Subretinal Yellow Deposits Following Cytostatic Therapy for Ear...
Dias-Santos, A; Lemos, V; Ferreira, J; Cunha, JP; Branco, JIntroduction/Objective: To report a case of ocular toxicity related to two chemotherapeutic regimens approved for early-stage breast cancer: doxorubicin (Adriamycin®) and cyclophosphamide – AC protocol; carboplatin and docetaxel combination. Material and Methods: We report a case of a 39-year-old woman with stage I ductal invasive breast cancer, who presented with bilateral painless reduced visual acuity two da...
Pseudo-aneurisma traumático da artéria carótida interna como causa de epistaxis
Guimarães, A; Freire, F; Vilela, P; Branco, G; Lemos, V; Prata, JO pseudo-aneurisma traumático da carótida interna é uma das causas raras de epistaxis, que pode ser fatal se não diagnosticado e tratado atempadamente. Os autores relatam o caso clínico de um jovem com pseudo-aneurisma da carótida interna que se apresentou com epistaxis grave, 11 anos após traumatismo crânio-facial. Foi feita embolização do pseudo-aneurisma com coils, com sucesso e sem sequelas neurológicas.