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Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a ...

Braga,Vanessa Nogueira Lages; Juanes,Camila de Carvalho; Peres Júnior,Hélio de Souza; Sousa,José Robson de; Cavalcanti,Bruno Coêlho

Abstract Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week for 2 weeks, animals on control groups received saline, while animals in experimental groups received azoxymethane (15 mg/kg i.p.). The follow up along ...

Date: 2019   |   Origin: Oasisbr

Effect of red propolis on hamster cheek pouch angiogenesis in a new sponge impl...

Melo,Nayanna de Oliveira Ramos; Juanes,Camila de Carvalho; Alves,Mayara Freire de Alencar; Silva,Emiliano Tiago Melo

Abstract Purpose: To evaluate the effects of red propolis on cheek pouch angiogenesis in a hamster new model sponge implant. Methods: Forty eight animals divided into eight groups. (Groups I-IV), the animals were treated for 15 days before and 10 days after sponge implantation. (Groups V-VIII), the animals were treated for 10 days after sponge implantation (GI and GV: red propolis 100 mg/kg, GII and GVI: celeco...

Date: 2018   |   Origin: Oasisbr

Chemoprevention with green propolis green propolis extracted in L-lysine versus...

Dornelas,Conceição Aparecida; Fechine-Jamacaru,Francisco Vagnaldo; Albuquerque,Irineu Lima; Magalhães,Hemerson Iury Ferreira

PURPOSE: To determine the effects of green propolis extracted in L-lysine (WSDP) and of L- lysine for 40 weeks on induced rat bladder carcinogenesis. METHODS: The animals (groups I, II, III, IV, V and VI) received BBN during 14 weeks. Group I was treated with propolis 30 days prior received BBN, and then these animals were treated daily with propolis; Groups II and III was treated with subcutaneous and oral pro...

Date: 2012   |   Origin: Oasisbr

Angiogenesis inhibition by green propolis and the angiogenic effect of L-lysine...

Dornelas,Conceição Aparecida; Fechine-Jamacaru,Francisco Vagnaldo; Albuquerque,Irineu Lima; Magalhães,Hemerson Iury Ferreira; Dias,Thiago Alves

PURPOSE: To determine the effects of water-soluble derivative of green propolis in bladder cancer angiogenesis in rats given N-butyl-(-4-hydroxybutyl) nitrosamine (BBN). METHODS: Nine groups were established, where six of them (Groups 1 to 6), the animals received 0.05% BBN in their drinking water for 14 weeks. From the 32nd to the 40th week, Groups 1, 2, 3 and 4 were treated respectively with water, L-lysine (...

Date: 2012   |   Origin: Oasisbr

Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegyp...

Vasconcelos,Jackson Nunes e; Santiago,Gilvandete Maria Pinheiro; Lima,Jefferson Queiroz; Mafezoli,Jair; Lemos,Telma Leda Gomes de

In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers., against Aedes aegypti, the main vector of dengue. The absolute configuration of these compounds was determined by circular dichroism (CD) spectra. The LC50 values ...

Date: 2012   |   Origin: Oasisbr

Estudo químico de uma amostra de própolis verde de Passa Quatro, Minas Gerais, ...

Tavares,Leonardo Carvalho; Lemos,Telma Leda Gomes de; Arriaga,Angela Martha Campos; Santiago,Gilvandete Maria Pinheiro; Braz-Filho,Raimundo

The phytochemical investigation of a sample of propolis from Passa Quatro-Minas Gerais State, Brazil, where nine constituents were isolated: a mixture of α- and β-amyrin, lupeol, a mixture of flavonols ramnocitrin and eupalitin, acacetin, 3-prenyl-4-hydroxycinnamic acid, 3,5-diprenyl-4-hydroxycinnamic acid the new compound, the (E)-3-[4-(3-phenylpropanoiloxy)]-3,5-diprenil-cinnamic acid. The structures of the i...

Date: 2010   |   Origin: Oasisbr

Avaliação de macro e microminerais em frutas tropicais cultivadas no nordeste b...

Almeida,Maria Mozarina Beserra; Sousa,Paulo Henrique Machado de; Fonseca,Maria Luciana; Magalhães,Carlos Emanuel Carvalho; Lopes,Maria de Fátima Gomes

O Brasil tem grande importância no mercado de frutas; porém há escassez de dados acerca da composição das frutas tropicais brasileiras, principalmente daquelas produzidas no nordeste. No presente estudo, determinaram-se macro e microminerais de 11 frutas tropicais cultivadas no nordeste brasileiro: abacaxi, ata, graviola, jaca, mamão, mangaba, murici, sapoti, seriguela, tamarindo e umbu. As amostras foram desid...

Date: 2009   |   Origin: Oasisbr

Estudo químico e biológico de Tephrosia toxicaria Pers.

Vasconcelos,Jackson Nunes e; Lima,Jefferson Queiroz; Lemos,Telma Leda Gomes de; Oliveira,Maria da Conceição Ferreira de; Almeida,Maria Mozarina Beserra

The ethanol extracts from leaves, stems, pods and roots were assayed against the 3rd instar Aedes aegypti larvae and the highest activity was observed in the roots extracts (LC50 47.86 ppm). This extract was submitted to partition with hexane, chloroform, ethyl acetate and methanol. The respective fractions were bioassayed and the best larvicidal activities were identified in the hexane (LC50 23.99 ppm) and chl...

Date: 2009   |   Origin: Oasisbr

Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn ...

Salgado,Alexandre Daher Yunes; Maia,Juliana Lemos; Pereira,Sérgio Luís da Silva; Lemos,Telma Leda Gomes de; Mota,Olívia Morais de Lima

OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or place...

Date: 2006   |   Origin: Oasisbr

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